Results 131 to 140 of about 3,624 (150)

Role of E3 Ubiquitin Ligases in Oligodendrocyte Health and Disease. [PDF]

ASN Neuro
Mabb AM, Pyaram DN, Samanta J.
europepmc   +1 more source

SEL1L regulates ER homeostasis in Sertoli cells but is dispensable for their function. [PDF]

Mol Biol Cell
Tushi NJ, Lu Y, Zhang Z, Sun S.
europepmc   +1 more source

Protein sorting and proteostasis mechanisms in CFTR-related exocrine pancreas dysfunction: A systematic narrative review. [PDF]

Channels (Austin)
Niyomugabo AP, Ntakirutimana L, Alagbonsi AI.   +2 more
europepmc   +1 more source

Endoplasmic reticulum stress in Hashimoto's thyroiditis: a candidate amplification node linking thyroid-specific vulnerability and immune dysregulation. [PDF]

Front Immunol
Si X, Guo Z, Jiao G, Zhang X, Ge Y, Qian J, Li X, Geng W, Yao S, Ding Z, Wu Y.   +10 more
europepmc   +1 more source

PERK signaling maintains hematopoietic stem cell pool integrity under endoplasmic reticulum stress by promoting proliferation.

Blood
Zheng M, Peng Q, Kropp EM, Shen Z, Liu S, Yin Z, Matono S, Iwawaki T, Wang X, Inoki K, Mei Y, Li Q, Liu L.   +12 more
europepmc   +1 more source

Characterization of protein complexes of the endoplasmic reticulum-associated degradation E3 ubiquitin ligase Hrd1 [PDF]

Journal of Biological Chemistry, 2017
Hrd1 is the core structural component of a large endoplasmic reticulum membrane-embedded protein complex that coordinates the destruction of folding-defective proteins in the early secretory pathway.
Ron Kopito, James Olzmann, Joshua E Elias   +2 more
exaly   +2 more sources

Derlin2 Protein Facilitates HRD1-mediated Retro-translocation of Sonic Hedgehog at the Endoplasmic Reticulum*

Journal of Biological Chemistry, 2013
[[abstract]]Endoplasmic reticulum-associated degradation (ERAD) is an important system that eliminates misfolded proteins from the ER. Three derlins have been implicated in this process, but their precise function remains unknown.
Yihong Ye
exaly   +2 more sources

Herp Regulates Hrd1-mediated Ubiquitylation in a Ubiquitin-like Domain-dependent Manner*

Journal of Biological Chemistry, 2011
Accumulation of aberrant proteins in the endoplasmic reticulum (ER) triggers the unfolded protein response pathway that helps the cell to survive under these stress conditions.
Melanie Kny, Rasmus Hartmann-Petersen
exaly   +2 more sources

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin. [PDF]

Journal of Neurochemistry, 2006
It has been proposed that in autosomal recessive juvenile parkinsonism (AR-JP), a ubiquitin ligase (E3) Parkin, which is involved in endoplasmic reticulum-associated degradation (ERAD), lacks E3 activity.
Tomohiro Omura, Masayuki Kaneko
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Role of the E3 ubiquitin ligase HRD1 in the regulation of serotonin transporter function

Biochemical and Biophysical Research Communications, 2021
Masayuki Kaneko, Norio Sakai
exaly