Results 161 to 170 of about 18,813 (211)

Protein kinase Cδ and pharmacomechanical coupling: Re-envisioning cerebral vascular control. [PDF]

open access: yesJ Physiol
Haghbin N   +10 more
europepmc   +1 more source

Altered Cross-Linking of HSP27 by Zerumbone as a Novel Strategy for Overcoming HSP27-Mediated Radioresistance

open access: yesInternational Journal of Radiation Oncology Biology Physics, 2011
HSP27 or HSP25 negatively regulates apoptosis pathways after radiation or chemotherapeutic agents. Abrogation of HSP27 function may be a candidate target for overcoming radio- and chemoresistance.Zerumbone (ZER), a cytotoxic component isolated from Zingiber zerumbet smith.
Joo-Won Nam   +2 more
exaly   +4 more sources

On the role of Hsp27 in regulating apoptosis

Apoptosis: an International Journal on Programmed Cell Death, 2003
Heat shock proteins (Hsps) comprise several different families of proteins that are induced in response to a wide variety of physiological and environmental insults. One such protein which is highly induced during the stress response is a 27-kDa protein, termed Hsp27 whose expression is seen to correlate with increased survival in response to cytotoxic
Adrienne M Gorman, Afshin Samali
exaly   +3 more sources

The interaction and cellular localization of HSP27 and ERβ are modulated by 17β-estradiol and HSP27 phosphorylation

Molecular and Cellular Endocrinology, 2007
Recently, we identified heat shock protein 27 (HSP27) as an estrogen receptor-beta (ERbeta) associated protein that acts as a co-repressor of estrogen signaling and serves as a biomarker of atherosclerosis. In this study, we sought to further characterize the subcellular interaction of HSP27 and ERbeta, as well as explore the factors that may modulate ...
William T. Gerthoffer   +2 more
exaly   +3 more sources

HSP27 protects against ferroptosis of glioblastoma cells

Human Cell, 2021
Ferroptosis, as an new form of non-apoptotic regulated cell death, plays an important role in human cancers. Although it is reported that HSP27 is an novel regulator of ferroptosis in cancer, it remains unknown how HSP27 affects ferroptosis in glioma. In this study, we examined the effect of HSP27 on the ferroptosis of glioblasotma.
Baohui Liu, Qianxue Chen, Yang Xu
exaly   +3 more sources

The protective role of HSP27 in ocular diseases

Molecular Biology Reports, 2022
Heat shock proteins (HSPs) are stress-induced proteins that are important constituents of the cell's defense system. The activity of HSPs enhances when the cell undergoes undesirable environmental conditions like stress. The protective roles of HSPs are due to their molecular chaperone and anti-apoptotic functions.
K, Sooraj   +4 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy