Results 111 to 120 of about 86,733 (300)
Plant Protection Science, 2013 Changes in Hsp70 gene expression and protein level were studied in three Solanum spp. genotypes in response to short-term high and low temperatures and to infection by powdery mildew.
Lucie KUBIENOVÁ +8 more
doaj +1 more source
Influence of tumors on protective anti-tumor immunity and the effects of irradiation [PDF]
, 2013 Innate and adaptive immunity play important roles in the development and progression of cancer and it is becoming apparent that tumours can influence the induction of potentially protective responses in a number of ways.
Alan Graham Pockley +6 more
core +2 more sources
Equine Veterinary Journal, EarlyView.Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska +4 more
wiley +1 more source
Functions and Therapeutic Use of Heat Shock Proteins in Hepatocellular Carcinoma
LiversHeat shock proteins are intracellular proteins expressed in prokaryotes and eukaryotes that help protect the cell from stress. They play an important role in regulating cell cycle and cell death, work as molecular chaperons during the folding of newly ...
Ramakrushna Paul +6 more
doaj +1 more source
Heat shock protein 70 (HSP70) induces cytotoxicity of T-helper cells
Blood, 2009 Abstract Heat shock protein 70 (HSP70) has gained plenty of attention because of its adjuvant capability to induce CD8+ cytotoxic T lymphocyte and CD4+ T-helper cell responses. We investigated the behavior of T-cell subsets stimulated with endotoxin-free HSP70 with respect to proliferation, cytokine expression, cytotoxicity against ...
Figueiredo, Constanca +6 more
openaire +3 more sources
Food Safety and Health, EarlyView.Heat‐stressed soybeans adapt to elevated temperatures through coordinate regulation of destructive and protective protein expression ‐ suppressing detrimental proteins while enhancing beneficial ones. ABSTRACT Soybean represents the largest imported agricultural product in China. Imported soybeans are typically transported via maritime shipping. During
Pengdi Ding +5 more
wiley +1 more source
DnaK duplication and specialization in bacteria correlates with increased proteome complexity
mSystemsThe chaperone 70 kDa heat shock protein (Hsp70) is important for cells from bacteria to humans to maintain proteostasis, and all eukaryotes and several prokaryotes encode Hsp70 paralogs.
Zhuo Pan +4 more
doaj +1 more source
The refolding activity of the yeast heat shock proteins Ssa1 and Ssa2 defines their role in protein translocation. [PDF]
, 1996 Ssa1/2p, members of one of the yeast cytosolic hsp70 subfamilies, have been implicated in the translocation of secretory proteins into the lumen of the ER.
Bush, GL, Meyer, DI
core
Aging cellular networks: chaperones as major participants
, 2006 We increasingly rely on the network approach to understand the complexity of cellular functions. Chaperones (heat shock proteins) are key "networkers", which have among their functions to sequester and repair damaged protein. In order to link the network
Agoston +56 more
core +1 more source
Natural killer cell response to chemotherapy-stressed cancer cells: Role in tumor immunosurveillance. [PDF]
, 2017 Natural killer (NK) cells are innate cytotoxic lymphoid cells that actively prevent neoplastic development, growth, and metastatic dissemination in a process called cancer immunosurveillance.
Borrelli, Cristiana +5 more
core +1 more source