Results 121 to 130 of about 86,733 (300)

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, EarlyView.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Pulsed Electromagnetic Fields: A Novel Attractive Therapeutic Opportunity for Neuroprotection After Acute Cerebral Ischemia

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Acute cerebral ischemia is characterized by several pathological processes evolving during time, which contribute to the final tissue damage. Secondary processes, such as prolonged inflammatory response, impaired mitochondrial function and oxidative stress, are responsible for the progression of brain injury to the peri‐infarct area,
Fioravante Capone, Simona Salati, Fabrizio Vincenzi, Micaela Liberti, Giorgio Aicardi, Francesca Apollonio, Katia Varani, Ruggero Cadossi, Vincenzo Di Lazzaro   +8 more
wiley   +1 more source

Production and immune response of recombinant Hsp60 and Hsp70 from the salmon pathogen Piscirickettsia salmonis

Biological Research, 2005
We have isolated and sequenced the genes encoding the heat shock proteins 60 (Hsp60) and 70 (Hsp70) of the salmon pathogen Piscirickettsia salmonis. The sequence analysis revealed the expected two open reading frames that encode proteins with calculated ...
VIVIAN WILHELM, CRISTIÁN SOZA, RODRIGO MARTÍNEZ, MARIO ROSEMBLATT, LUIS O BURZIO, PABLO D.T. VALENZUELA   +5 more
doaj  

Expression of Hsp70 and β-actin Genes as The Immune Response against Viral Nervous Necrosis that Infected Asian Seabass (Lates calcalifer)

Journal of Experimental Life Science, 2018
The viral nervous necrosis (VNN) is betanodavirus of the family Nodaviridae with acute infection and associated with high levels mortality up to 100% of numerous larval-stage marine and freshwater fish species.
Yusuf Arif Wahyudi, Uun Yanuhar, Maftuch Maftuch   +2 more
doaj   +1 more source

DAMPs and PDT-mediated photo-oxidative stress: exploring the unknown [PDF]

, 2011
Damage-associated molecular patterns (DAMPs) or cell death associated molecular patterns (CDAMPs) are a subset of endogenous intracellular molecules that are normally hidden within living cells but become either passively released by primary and ...
Agostinis, Patrizia, Garg, Abhishek D, Krysko, Dmitri, Vandenabeele, Peter   +3 more
core   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Genomic analysis, evolution and characterization of the heat shock protein-70 gene family in foxtail millet [Setaria italica (L.) P.Beauv.] along with expression analysis under saline conditions

International Journal of Applied and Experimental Biology
Under stress conditions, heat shock proteins (HSPs) serve as fundamental regulators of cellular homeostasis. The molecular chaperone HSP70 belongs to a group of stress-related proteins which play important roles across growth and developmental events ...
Jawad Ali, Ali Raza, Muhammad Aakif Khan, Aqib Zeb, Maliha Ghaffar, Maqsood Ahmed Khaskheli   +5 more
doaj   +1 more source

Lead-induced heat shock protein (HSP70) and metallothionein (MT) gene expression in the embryos of African catfish Clarias gariepinus (Burchell, 1822)

Scientific African, 2019
The enhanced expression of heat shock proteins (HSPs) and metallothionein (MT) can be detected in response to many environmental stressors, including exposure to heavy metals. We identified partial mRNA sequences for beta2-microglobulin (ß2m), heat shock
Alaa G.M. Osman, Sven Wuertz, Khaled Mohammed-Geba   +2 more
doaj   +1 more source

Heat shock protein 70-2 (HSP70-2) overexpression in breast cancer

Journal of Experimental & Clinical Cancer Research, 2016
Breast cancer is one of the leading cause of cancer-related deaths in women worldwide and increasing rapidly in developing countries. In the present study, we investigated the potential role and association of HSP70-2 with breast cancer.HSP70-2 expression was examined in 154 tumor and 103 adjacent non-cancerous tissue (ANCT) specimens and breast cancer
Jagadish, Nirmala, Agarwal, Sumit, Gupta, Namita, Fatima, Rukhsar, Devi, Sonika, Kumar, Vikash, Suri, Vaishali, Kumar, Rajive, Suri, Vitusha, Sadasukhi, Trilok Chand, Gupta, Anju, Ansari, Abdul S., Lohiya, Nirmal Kumar, Suri, Anil   +13 more
openaire   +2 more sources

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source