Results 141 to 150 of about 55,389 (309)

The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB

, 2006
The tight junction adaptor protein ZO-1 regulates intracellular signaling and cell proliferation. Its Src homology 3 (SH3) domain is required for the regulation of proliferation and binds to the Y-box transcription factor ZO-1-associated nucleic acid ...
Balda, MS, Matter, K, Tsapara, A
core  

Peptide‐based responsive molecular fluorescent probes for precision oncology

Responsive Materials, EarlyView.
Peptide‐based responsive fluorescent probes have emerged as adaptive functional materials for precision tumor theranostics, combining tumor‐selective recognition, programmable stimulus responsiveness, and modular tunability. They enable high‐contrast imaging, intraoperative guidance, real‐time monitoring, and multimodal applications, while next ...
Xing Wang, Wen Liu, Jiahao Zhang, Wanqi Wang, Zhicheng Jin, Yuqi Tang, Quan Li   +6 more
wiley   +1 more source

Genome-wide transcriptomic analysis reveals autophagy and HSP70-mediated mechanisms underlying thermal stress adaptation in Mytilus coruscus

BMC Genomics
Rising ocean temperatures driven by global warming pose a major threat to marine organisms. In this study, we examined physiological and molecular changes in the muscle, gill, foot, and mantle tissues of Mytilus coruscus under thermal stress ...
Chao Li, Siying Lv, Hua Jing, Heng Zhou, Xiao Liu   +4 more
doaj   +1 more source

Influence of Age and Exposure Pathway on Copper and Cadmium Mixture Toxicity: A Study on Daphnia magna

Environmental Toxicology, EarlyView.
ABSTRACT Metal contamination in aquatic ecosystems poses substantial risks to freshwater organisms, with mixture effects often deviating from predictions based on single‐metal toxicity. Understanding how age‐specific sensitivities and multiple exposure pathways influence mixture effects is critical for accurate risk assessment.
Sanah Majid, Karen Smeets, Mubiana K. Valentine, Ronny Blust   +3 more
wiley   +1 more source

The heat shock proteins (Hsps). II. Hsp70: biomarker and actor of cellular stress [PDF]

, 2003
peer reviewedThe exposure of any organism to high temperature induces rapid and transient cellular overexpression of specific proteins, the heat shock proteins (Hsps). This response, called heat shock response, was initially discovered in Drosophila. The
Gustin, Pascal, Christiaens, E., Wirth, Delphine, Dessy, Cécile, Drion, Pierre   +4 more
core  

Plasma Proteomics Analysis Identifying IGFBP2 as a Potential Diagnostic Biomarker for Laryngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng, Ling‐Mei Qu, Jun‐Jie Liu, Yu‐Shan Li, Zi‐Qi Chen, Shuo Liu, Zhao‐Nan Xu, Meng Jin, Qiu‐Ying Li, Qin Wu, Hong‐Tian Yi, Xian‐Ji Shen, Bing‐Rui Yan, Ya‐Nan Sun   +13 more
wiley   +1 more source

A Survey of Heat Shock Protein Length Variation Within and Between Species of Drosophila [PDF]

, 1987
Forty iso-females lines of Drosophila melanogaster were surveyed by SDS-PAGE for length polymorphisms in their heat shock proteins. None was observed. The 70K and 27K HSP's were further analyzed by peptide mapping using Staphylococcus aureas va protease,
McMillan, William
core  

Expression of hsrω-RNAi transgene prior to heat shock specifically compromises accumulation of heat shock-induced Hsp70 in Drosophila melanogaster

, 2015
A delayed organismic lethality was reported in Drosophila following heat shock when developmentally active and stress-inducible noncoding hsrω-n transcripts were down-regulated during heat shock through hs-GAL4-driven expression of the hsrω-RNAi ...
Singh, Anand K., Lakhotia, Subhash C.
core   +1 more source

The Effects of Noise on the Juvenile Life Stage of Crustaceans: Behavioral, Cellular, and Molecular Responses in Procambarus clarkii

Integrative Zoology, EarlyView.
Juvenile Procambarus clarkii exposed to noise exhibited behavioral changes, shifts in enzymatic activity, and altered expression of stress and immune genes. The findings highlight the sensitivity of invertebrate juveniles to anthropogenic acoustic pollution.
Maria Ceraulo, Giuseppa Buscaino, Clarissa De Vita, Aiti Vizzini, Mirella Vazzana, Elena Papale, Francesco Longo, Francesco Paolo Faraone, Manuela Mauro   +8 more
wiley   +1 more source

Polypropylene Nanoplastic Exposure to Respiratory Epithelial Barrier‐On‐Chip and Interfacial Interactions With Human Serum Albumin

Allergy, EarlyView.
Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert, Eyup Bilgi, Reyhan Coban, Pelin Saglam‐Metiner, Basar Dogan, Zeynep Imir‐Tekneci, Suleyman Selim Cinaroglu, Ozlem Goksel, Ceyda Oksel Karakus, Ozlem Yesil‐Celiktas   +9 more
wiley   +1 more source