Results 161 to 170 of about 50,507 (259)

Autophagy in MASLD: A Metabolic and Precision Medicine Perspective

open access: yesLiver International, Volume 46, Issue 9, September 2026.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga   +4 more
wiley   +1 more source

RGF signaling bridges root development and nonlethal thermal stress adaptation

open access: yesNew Phytologist, Volume 251, Issue 5, Page 2656-2671, September 2026.
Nonlethal high temperature inhibits root growth. Summary Roots adapt to growth‐restricting but nonlethal high temperatures. Although lethal heat shock and moderately elevated temperatures have been extensively studied, the effects of nonlethal thermal stress on root development remain unclear.
Yu‐Chun Hsiao   +3 more
wiley   +1 more source

CPTCs Drive Somatic‐Visceral Communication via the Wnt Axis in Somatic Mechanotherapy: A Single‐Cell Deep Learning Study

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Using an interpretable deep learning framework (CARSS) applied to multi‐tissue single‐cell RNA sequencing, we identify CD34⁺PDGFRα⁺ telocytes (CPTCs) as the primary mechanosensors bridging somatic acupuncture stimulation and visceral repair. Mechanical force at acupoints activates an AP‐1/Hsp70 immediate‐early gene program in fascial CPTCs, triggering ...
Haixiang Huang   +12 more
wiley   +1 more source

Evaluation of Hsp70 and Apoptotic Markers in Canine Cutaneous Lupus Erythematosus. [PDF]

open access: yesVet Sci
Magi GE   +5 more
europepmc   +1 more source

HOF‐Stabilized Apple EV Nanocargo in an NIR‐Responsive Hydrogel Enables On‐Demand Therapeutic Modulation for Transdermal Deep‐Joint Osteoarthritis Therapy

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 29, 7 August 2026.
An NIR‐responsive transdermal hydrogel integrating apple EV nanocargo, berberine, piperine, HOFs, and graphene oxide enables localized osteoarthritis modulation. The platform supports enhanced transdermal delivery together with mild hyperthermia‐associated and redox‐related responses, leading to reduced inflammation and oxidative stress, improved ...
Yu‐Wen Tseng   +9 more
wiley   +1 more source

Hsp70s regulate circadian rhythm by interacting with PERIOD. [PDF]

open access: yesCell Commun Signal
Zhao X   +6 more
europepmc   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

open access: yesAdvanced Intelligent Discovery, Volume 2, Issue 4, August 2026.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz   +2 more
wiley   +1 more source

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