Results 161 to 170 of about 55,389 (309)
Heat death and the development of thermotolerance in the blow fly calliphora viicina: a study of flight muscle mitochondrial function [PDF]
, 1996 The LD(_50) of 10-day-old blowflies differed significantly in two different stocks, and were found to be 38.12 ± 0.07ºC for the Durham stock and 40.8 ± 0.18ºC for the Cambridge stock.
El-Wadawi, Rukaya A.
core
Proteostasis of organelles in aging and disease
The FEBS Journal, EarlyView.Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi +5 more
wiley +1 more source
The heat shock response of Mycobacterium tuberculosis: linking gene expression, immunology and pathogenesis [PDF]
, 2002 Joseph A. Mangan +16 more
core +1 more source
, 2005 In contrast to the class A heat stress transcription factors (Hsfs) of plants, a considerable number of Hsfs assigned to classes B and C have no evident function as transcription activators on their own.
Bharti, Kapil
core
KU80 suppresses endonuclease G activity to preserve genomic integrity
The FEBS Journal, EarlyView.Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan +8 more
wiley +1 more source
The FEBS Journal, EarlyView.Evolutionary and mechanistic divergence in the Hsp70–Hsp110 chaperone system. Prokaryotic Hsp70s probably diversified into multiple orthologues that cooperated with co‐chaperones such as JDPs and NEF, forming increasingly complex proteostasis networks.
Pierre Goloubinoff +2 more
wiley +1 more source
The FEBS Journal, EarlyView.Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma +1 more
wiley +1 more source
The functional analysis of heat shock proteins HSP90 and HSP70 in animal retinas.
, 1995 The functional analysis of heat shock proteins HSP90 and HSP70 in animal ...
Seunghee. Kim-Schulze (7952516)
core
Biogenesis of TNF‐α‐insights into proteostasis and inflammation
The FEBS Journal, EarlyView.TNF‐α biogenesis, trafficking, and signalling are tightly and reciprocally coupled to cellular proteostasis systems, including ER chaperones and endoplasmic reticulum‐associated degradation. This bidirectional crosstalk determines whether TNF‐α responses are adaptive or proteotoxic.
Bailasan Haidar +3 more
wiley +1 more source