Results 221 to 230 of about 170,313 (323)

Endogenous oestrogens as neuroprotective modulators in the human retina: Evidence from transcriptomic profiling and aromatase inhibition

Journal of Neuroendocrinology, Volume 38, Issue 4, April 2026.
Single‐cell transcriptomics reveals that the human retina expresses a broad repertoire of steroid hormone biosynthesis and estrogen signalling genes. Functional validation in retinal explants shows that local estrogen synthesis is neuroprotective, preventing photoreceptor death and limiting microglial activation. Abstract Steroid hormones, particularly
Antolin Canto, Javier Valero‐Ochando, Rosa López‐Pedrajas, Teresa Olivar, Vicente Hernández‐Rabaza, Inmaculada Almansa, María Miranda   +6 more
wiley   +1 more source

Lipid interaction differentiates the constitutive and stress-induced heat shock proteins Hsc70 and Hsp70

Cell stress & chaperones (Print), 2002
N. Arispe, M. Doh, A. De Maio
semanticscholar   +1 more source

Circular RNA Vv‐circCOR27 modulates thermotolerance through attenuating VvHSP90.2b‐VvHsfA7a interaction in grapevine

New Phytologist, Volume 250, Issue 2, Page 988-1003, April 2026.
Summary Circular RNAs (circRNAs) are single‐stranded, covalently closed RNA molecules that arise from exon back‐splicing. The identification and function investigation of circRNAs have been comprehensively explored in plants, however, the regulatory mechanisms are largely unknown.
Yi Ren, Yuanyuan Xu, Moyang Liu, Lipeng Zhang, Yue Song, Junpeng Li, Jingjing Liu, Dongying Fan, Zhen Zhang, Juan He, Jiuyun Wu, Qian Zha, Zhen Gao, Zheng'an Yang, Chao Ma   +14 more
wiley   +1 more source

HSP-1-specific nanobodies alter chaperone function in vitro and in vivo. [PDF]

J Biol Chem
Urban ND, Gharat K, Mattiola ZJ, Scheutzow A, Klaiss A, Tabler S, Huffaker AW, Grootveld M, Skinner ME, Zheng W, O'Meara MJ, Kirstein J, Truttmann MC.   +12 more
europepmc   +1 more source

Saturation, Competition, and Specificity in Interaction of Heat Shock Proteins (hsp) gp96, hsp90, and hsp70 with CD11b+ Cells1

Journal of Immunology, 2000
R. Binder, M. L. Harris, A. Ménoret, P. Srivastava   +3 more
semanticscholar   +1 more source

Disulfide Crosslinking Induces Rapid Degradation of Arc/Arg3.1 via Hsp70‐Mediated Ubiquitin Ligase Pathway

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Heat shock induces Arc/Arg3.1 Cys34‐Cys159 disulfide crosslinking, promoting oligomerization and Hsp70‐CHIP‐dependent ubiquitination followed by proteasomal degradation during recovery. Disrupting disulfide formation (C159A) impairs CHIP‐mediated ubiquitination and stabilizes Arc/Arg3.1, whereas HSF1 loss limits inducible Hsp70 and leads to Arc ...
Dami So, In‐Kang Song, Yeon Jung Kim, Yeonjoo Lee, Yeon Seung Park, Hee‐Jung Kim, Kong‐Joo Lee, Eun Joo Song   +7 more
wiley   +1 more source

Hypertension and Diabetes Cooperatively Drive HSP90 Activation, HSP70 Suppression, and Left Ventricular Interstitial Expansion: Relevance to Maladaptive Myocardial Remodeling. [PDF]

Pathophysiology
Sklifasovskaya AP, Blagonravov ML, Azova MM, Kurevlev SV, Goryachev VA, Syatkin SP, Zotova TY, Prokofiev DY.   +7 more
europepmc   +1 more source

Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-kappa B pathway.

International Immunology, 2000
Sreyashi Basu, R. Binder, R. Suto, K. M. Anderson, P. Srivastava   +4 more
semanticscholar   +1 more source

Probiotic Bifidobacterium Confers Protection Against Heat Stroke Through Enhancement of Intestinal Barrier Function in Rats. [PDF]

Shock
Cai G, Chen Y, Chen J, Zhang J, Cai J, Fan Q, Zhang Y, Tang Y, Huang J, Xia G, Wang C, Feng A, Nie X.   +12 more
europepmc   +1 more source

Heat Shock Proteins gp96 and hsp70 Activate the Release of Nitric Oxide by APCs1

Journal of Immunology, 2002
Naveed N. Panjwani, Lana Popova, P. Srivastava   +2 more
semanticscholar   +1 more source