Results 251 to 260 of about 138,190 (352)
Selective depletion of tumor-associated SAMHD1 enhances chemotherapeutic efficacy and antitumor immune responses. [PDF]
Sun J +29 more
europepmc +1 more source
Potential role of heat shock protein 90 (Hsp90) in HIV uncoating [PDF]
Pheroze Joshi, Cheryl A. Stoddart
openalex +1 more source
RCCD1 is upregulated in colon cancer and cancer‐associated fibroblasts (CAFs). In CAFs, RCCD1 overexpression activates AMPK/mTOR/ULK1 signaling, enhancing autophagy. This stimulates autophagic secretion of WNT5A. WNT5A then activates the nonclassical Wnt/CaMKII/ERK pathway in tumor cells, promoting epithelial‐mesenchymal transition (EMT), proliferation,
Chao Liu +3 more
wiley +1 more source
<i>Plasmodium knowlesi</i> Heat Shock Protein 90s: <i>In Silico</i> Analysis Reveals Unique Druggable Structural Features. [PDF]
Daniyan MO, Singh H, Blatch GL.
europepmc +1 more source
NudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90
Yuehong Yang +5 more
openalex +1 more source
The Secretome of Human Trophoblast Stem Cells Attenuates Senescence‐Associated Traits
Human trophoblast stem cell‐derived secretome/conditioned medium (hTSC‐CM) and the extracellular vesicles (EVs) therein suppress DNA damage and NF‐κB activation in senescent fibroblasts, in turn reducing the production of senescence‐associated secretory phenotype (SASP) factors. This study highlights hTSC‐CM and EVs as potential senotherapeutic agents.
Kotb Abdelmohsen +18 more
wiley +1 more source
Targeting the protein-protein interaction between the CDC37 cochaperone and client kinases by an allosteric RAF dimer breaker. [PDF]
Yu A +5 more
europepmc +1 more source

