Results 251 to 260 of about 138,190 (352)

Selective depletion of tumor-associated SAMHD1 enhances chemotherapeutic efficacy and antitumor immune responses. [PDF]

open access: yesSignal Transduct Target Ther
Sun J   +29 more
europepmc   +1 more source

Figure S1 from The HSP90 Inhibitor Pimitespib Targets Regulatory T Cells in the Tumor Microenvironment

open access: gold
Ayaka Tsuge   +16 more
openalex   +1 more source

Preface to Hsp90

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2012
openaire   +3 more sources

RCC1 Domain‐Containing Protein 1 Promotes Colon Cancer Malignant Progression by Activating Autophagy‐Dependent WNT5A Secretion in Cancer‐Associated Fibroblasts

open access: yesJournal of the Royal Society of New Zealand, Volume 56, Issue 1, February 2026.
RCCD1 is upregulated in colon cancer and cancer‐associated fibroblasts (CAFs). In CAFs, RCCD1 overexpression activates AMPK/mTOR/ULK1 signaling, enhancing autophagy. This stimulates autophagic secretion of WNT5A. WNT5A then activates the nonclassical Wnt/CaMKII/ERK pathway in tumor cells, promoting epithelial‐mesenchymal transition (EMT), proliferation,
Chao Liu   +3 more
wiley   +1 more source

NudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90

open access: green, 2010
Yuehong Yang   +5 more
openalex   +1 more source

The Secretome of Human Trophoblast Stem Cells Attenuates Senescence‐Associated Traits

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Human trophoblast stem cell‐derived secretome/conditioned medium (hTSC‐CM) and the extracellular vesicles (EVs) therein suppress DNA damage and NF‐κB activation in senescent fibroblasts, in turn reducing the production of senescence‐associated secretory phenotype (SASP) factors. This study highlights hTSC‐CM and EVs as potential senotherapeutic agents.
Kotb Abdelmohsen   +18 more
wiley   +1 more source

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