Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu +5 more
wiley +1 more source
Cellular Stress and Immune Activation in Celiac Disease: Is the Chaperone System a Key Player? [PDF]
Vergilio G +4 more
europepmc +1 more source
Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert +9 more
wiley +1 more source
Predicting Solubility Enhancement of <i>Trans</i>-Resveratrol and Hesperetin in Binary Solvent Mixtures Using New Hansen Parameters. [PDF]
Montenegro I +3 more
europepmc +1 more source
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu +8 more
wiley +1 more source
Maternal Heat Shock Protein as a Potential Biomarker of Adaptation to Heat Stress during Pregnancy and Its Relation to Preterm Birth. [PDF]
Yang X +20 more
europepmc +1 more source
Compartmentalisation in cAMP signalling: A phase separation perspective
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley +1 more source
Prognostic and clinicopathological significance of heat shock proteins in colorectal cancer patients: a meta-analysis. [PDF]
Wang Z, Zou J, Li Y, Zhang Z.
europepmc +1 more source
Heat Stress Triggers Nuclear Invagination and Spatial Compartmentalization of Protein Metabolism
Cells adapt heat stress to shape a nuclear invagination region function as “protein metabolism hotspots”, where both protein production and degradation are enhanced. ABSTRACT Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the highly conserved mechanism known as
Zhi‐Hao Zhang +11 more
wiley +1 more source
Evaluation of Hsp70 and Apoptotic Markers in Canine Cutaneous Lupus Erythematosus. [PDF]
Magi GE +5 more
europepmc +1 more source

