Results 161 to 170 of about 33,737 (296)
, 2013 杂交是改良种质的有效方法,杂交后代往往具有生长率、存活率、抗逆性方面的优势.为研究杂交对鲍的耐热性的影响,以皱纹盘鲍(HAlIOTIS dISCuS HAnnAI)、西氏鲍(HAlIOTIS gIgAnTEA)以及它们的正反交f1代为研究材料,以半定量PCr为研究手段研究了在梯度温度应激下,2种热休克蛋白(HSPS)在4个群体中的表达情况.实验结果表明,在正常温度下,西氏鲍具有最高的HSPS水平;在应激条件下,皱纹盘鲍的HSPS水平呈现先上升后下降的趋势,其他3个群体的HSPS水平均随温度上升而上升 ...
骆轩, 梁爽, 柯才焕, 游伟伟
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Cell Proliferation, EarlyView.Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li +6 more
wiley +1 more source
Photothermal-Responsive Phase Transition of Proteoliposomes for Heat Shock Protein Sequestering against Cancer Thermoresistance. [PDF]
Research (Wash D C)Cheng K +7 more
europepmc +1 more source
, 2018 Efforts to develop students' science literacy skills are not only through the process of learning in the classroom but can be done through various activities outside of teaching and learning activities in the classroom.
Cahyani, Dewi; IAIN Syekh Nurjati Cirebon +2 more
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Proteostasis of organelles in aging and disease
The FEBS Journal, EarlyView.Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi +5 more
wiley +1 more source
Emerging perspectives in proteostasis: bridging mechanisms and therapeutics for human diseases. [PDF]
Signal Transduct Target TherBorlepawar A +7 more
europepmc +1 more source
The FEBS Journal, EarlyView.High density multi‐electrode (HD‐MEA) systems enable detailed investigation of healthy and diseased brains in 2D and 3D. Here, we summarise the significance of single‐cell electrophysiology, advantages of the MEA systems with high spatio‐temporal resolution and a large number of recording sites, enabling complex network analysis.
Zehra Yagmur Erol +2 more
wiley +1 more source
An Exploratory Study of Heat Shock Protein Changes in Women with Unexplained Infertility. [PDF]
Int J Mol SciAlhalwachi Z +3 more
europepmc +1 more source
AMIODARONE INDUCES THE SYNTHESIS OF HSPS IN SACCHAROMYCES CEREVISIAE AND ARABIDOPSIS THALIANA CELLS
, 2012 Many biotic and abiotic stresses cause an increase of cytosolic Ca2+ level in cells. Calcium is one of the most important second messengers, regulating many various activities in the cell and was known to affect expression of stress activated genes. Mild
A.V. Stepanov +7 more
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Insect Conservation and Diversity, EarlyView.Burrows of the threatened Gibson's Big Sand Tiger Beetle in riverine dune habitats are susceptible to flooding through managed flows. HEC‐RAS modelling identified the flow thresholds above which flooding would occur for burrows and affect the beetle larvae. These findings provide instream flow guidelines for conserving this threatened species and guide
Iain D. Phillips +2 more
wiley +1 more source