Results 11 to 20 of about 51,748 (281)

Lysosome Function and Dysfunction in Hereditary Spastic Paraplegias

open access: yesBrain Sciences, 2021
Hereditary Spastic Paraplegias (HSPs) are a genetically diverse group of inherited neurological diseases with over 80 associated gene loci. Over the last decade, research into mechanisms underlying HSPs has led to an emerging interest in lysosome ...
Daisy Edmison   +2 more
doaj   +1 more source

Immunological aspects of heat shock protein functions and their significance in the development of cancer vaccines

open access: yesNowotwory, 2022
The primary function of intracellular heat shock proteins (HSPs) is to protect the cell by suppressing the effects of va­rious stress factors by either refolding misfolded proteins or blocking apoptosis. After neoplastic transformation, cells overexpress
Iryna Boliukh   +2 more
doaj   +1 more source

Ins and Outs of Heat Shock Proteins in Colorectal Carcinoma: Its Role in Carcinogenesis and Therapeutic Perspectives

open access: yesCells, 2021
Cancer cells can reprogram their metabolic activities and undergo uncontrolled proliferation by utilizing the power of heat shock proteins (HSPs). HSPs are highly conserved chaperones that facilitate the folding of intracellular proteins under stress ...
Batoul Abi Zamer   +3 more
doaj   +1 more source

Heat shock proteins and the cellular response to osmotic stress [PDF]

open access: yes, 2000
In antidiuresis, the intrarenal distribution of HSP25/27, alpha beta -crystallin, HSP72, OSP94 and HSP110 corresponds to the osmotic gradient between cortex and papilla: low amounts in the cortex and high values in the inner medulla and papilla.
Beck, Franz-X.   +3 more
core   +1 more source

Heat stress-induced changes in skeletal muscle: Heat shock proteins and cell signaling transduction

open access: yesJournal of Physical Fitness and Sports Medicine, 2012
Many researchers have been interested in the effects of heat stress on skeletal muscle. Recently, it has been demonstrated that heat stress on skeletal muscle results in an increase in muscle protein mass and subsequent muscle hypertrophy, and ...
Hisashi Naito   +4 more
doaj   +1 more source

Role of Heat Shock Proteins in Atrial Fibrillation: From Molecular Mechanisms to Diagnostic and Therapeutic Opportunities

open access: yesCells, 2022
Heat shock proteins (HSPs) are endogenous protective proteins and biomarkers of cell stress response, of which examples are HSP70, HSP60, HSP90, and small HSPs (HSPB).
Daiqi Liu   +5 more
doaj   +1 more source

Novel homozygous GBA2 mutation in a patient with complicated spastic paraplegia [PDF]

open access: yes, 2018
Hereditary spastic paraplegias (HSPs) are a heterogeneous group of neurological disorders characterized primarily by a pyramidal syndrome with lower limb spasticity, which can manifest as pure HSP or associated with a number of neurological or non ...
Bertini, Enrico   +10 more
core   +1 more source

HSP or not HSP… that is the question [PDF]

open access: yesBMJ Case Reports, 2010
The authors report on the case of a 10-year-old girl who presented with a vasculitic process primarily involving the skin, joints and kidneys, which was initially presumed to be a variant of Henoch-Schonlein purpura. When the disease process behaved in a more aggressive way than expected, with the rapid onset of acute renal failure, further ...
David, Cordiner   +2 more
openaire   +2 more sources

The effects of heat shock treatment on the floral formation of cucumber excised cotyledons and the electrophoresis patterns of soluble proteins(热击处理对离体子叶培养物花芽分化与可溶性蛋白谱的影响)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2001
黄瓜幼苗胚轴的不同部位对离体子叶培养物器官分化的影响是不同的.热击处理具不同长度胚轴的黄瓜幼苗,其子叶培养物的直接花芽分化率不同,其中以单去根处理的为最高,去根+去1/2胚轴的为最低,对照和去根+去3/4胚轴的居中.结果提示胚轴中存在着与成花有关的促进和/或抑制因子,热击无根苗产生了分子量约为67〜94 kD的热激蛋白.热击处理还使中性区域蛋白质含量下降.
LIFeng-yu(李凤玉)   +2 more
doaj   +1 more source

Stress protein (HSP70 family) expression in intertidal benthic organisms: the example of Anthopleura elegantissima (Cnidaria: Anthozoa)

open access: yesScientia Marina, 2004
Both the physiology and distribution of intertidal organisms are strongly influenced by different kinds of physical stress. Temperature, UV radiation and desiccation in low tide conditions are usually considered the most important physical stresses ...
Mark J. Snyder, Sergio Rossi
doaj   +1 more source

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