Results 21 to 30 of about 33,737 (296)

Heat shock proteins: Biological functions, pathological roles, and therapeutic opportunities

MedComm, 2022
The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect cells from stresses.
Chen Hu, Jing Yang, Ziping Qi, Hong Wu, Beilei Wang, Fengming Zou, Husheng Mei, Jing Liu, Wenchao Wang, Qingsong Liu   +9 more
doaj   +1 more source

Clinical Features and Genetic Spectrum of Patients With Clinically Suspected Hereditary Progressive Spastic Paraplegia

Frontiers in Neurology, 2022
Background and PurposeA variety of hereditary diseases overlap with neurological phenotypes or even share genes with hereditary spastic paraplegia (HSP).
Yuzhi Shi, An Wang, Bin Chen, Xingao Wang, Songtao Niu, Wei Li, Wei Li, Shaowu Li, Zaiqiang Zhang   +8 more
doaj   +1 more source

HSP expression depends on its molecular construction and different organs of the chicken: a meta-analysis

Scientific Reports, 2022
Heat shock proteins (HSPs) expression protect the cell from stress, this expression varies on tissue and stress level. Here, we investigated the structure and functional expression of HSPs in different chicken organs using meta-analysis.
Sharif Hasan Siddiqui, Mousumee Khan, Hosung Choe, Darae Kang, Kwanseob Shim   +4 more
doaj   +1 more source

Heat shock proteins as danger signals for cancer detection

Frontiers in Oncology, 2011
First discovered in 1962, heat shock proteins (HSPs) are highly studied with about 35,500 publications on the subject to date. HSPs are highly conserved, function as molecular chaperones for a large panel of client proteins and have strong cytoprotective
Renaud eSeigneuric, Renaud eSeigneuric, Hajare eMjahed, Hajare eMjahed, Jessica eGobbo, Jessica eGobbo, Anne-Laure eJoly, Anne-Laure eJoly, Kevin eBerthenet, Kevin eBerthenet, Sarah eShirley, Carmen eGarrido, Carmen eGarrido   +12 more
doaj   +1 more source

Traditional Chinese Medicine Targeting Heat Shock Proteins as Therapeutic Strategy for Heart Failure

Frontiers in Pharmacology, 2022
Heart failure (HF) is the terminal stage of multifarious heart diseases and is responsible for high hospitalization rates and mortality. Pathophysiological mechanisms of HF include cardiac hypertrophy, remodeling and fibrosis resulting from cell death ...
Yanchun Wang, Junxuan Wu, Dawei Wang, Rongyuan Yang, Qing Liu   +4 more
doaj   +1 more source

Heat Shock Proteins (Hsps) in Cellular Homeostasis: A Promising Tool for Health Management in Crustacean Aquaculture

, 2022
Heat shock proteins (Hsps) are a family of ubiquitously expressed stress proteins and extrinsic chaperones that are required for viability and cell growth in all living organisms. These proteins are highly conserved and produced in all cellular organisms
Kumar, Vikash, Bijay Behera, Das, Basanta Kumar, Roy, Suvra, Suvra Roy, Bijay Kumar Behera, Behera, Bijay Kumar, Basanta Das, Basanta Kumar Das, Vikash Kumar   +9 more
core   +1 more source

A Review on the Involvement of Heat Shock Proteins (Extrinsic Chaperones) in Response to Stress Conditions in Aquatic Organisms

Antioxidants, 2023
Heat shock proteins (HSPs) encompass both extrinsic chaperones and stress proteins. These proteins, with molecular weights ranging from 14 to 120 kDa, are conserved across all living organisms and are expressed in response to stress.
Sivakamavalli Jeyachandran, Hethesh Chellapandian, Kiyun Park, Ihn-Sil Kwak   +3 more
doaj   +1 more source

Different Heat Shock Proteins Bind α-Synuclein With Distinct Mechanisms and Synergistically Prevent Its Amyloid Aggregation

Frontiers in Neuroscience, 2019
α-Synuclein (α-Syn) forms pathological amyloid aggregates deposited in Lewy bodies and Lewy neurites in the brain of Parkinson’s disease (PD) patients.
Chunyu Jia, Chunyu Jia, Xiaojuan Ma, Xiaojuan Ma, Zhenying Liu, Zhenying Liu, Jinge Gu, Jinge Gu, Xiang Zhang, Xiang Zhang, Dan Li, Shengnan Zhang   +11 more
doaj   +1 more source

Comprehensive strategy of conduit guidance combined with VEGF producing Schwann cells accelerates peripheral nerve repair

Bioactive Materials, 2021
Peripheral nerve regeneration requires stepwise and well-organized establishment of microenvironment. Since local delivery of VEGF-A in peripheral nerve repair is expected to promote angiogenesis in the microenvironment and Schwann cells (SCs) play ...
Ping Wu, Zan Tong, Lihua Luo, Yanan Zhao, Feixiang Chen, Yinping Li, Céline Huselstein, Qifa Ye, Qingsong Ye, Yun Chen   +9 more
doaj   +1 more source

Heat Shock Proteins in Cardiovascular Stress

Clinical Medicine Insights: Cardiology, 2008
Heat shock proteins (HSPs) are primarily induced in response to stress stimuli. In cardiovascular diseases, HSPs are expressed pronouncedly and act to protect the cardiac tissue by inhibition of cellular apoptopic mechanisms.
John Geraldine, Sandana Mala, Satoru Takeuchi   +2 more
doaj   +1 more source