Results 171 to 180 of about 21,325,054 (309)

Triple‐Mutated HSV‐1 Expressing Soluble B7‐1 Plus CTLA‐4 Blockade Suppresses Lymph Node Metastasis in Tongue Cancer

Cancer Science, EarlyView.
In murine tongue cancer models, T‐mB7‐1, a triple‐mutated oncolytic herpes simplex virus type 1 (HSV‐1) engineered to express soluble B7‐1, suppresses cervical lymph node metastasis and improves survival, addressing a major prognostic determinant in oral squamous cell carcinoma (OSCC).
Akinari Sugauchi, Toshihiro Uchihashi, Hirotaka Ito, Miwako Iwai, Yuzuri Tsurumaki Sato, Kyoko Kurioka, Sena Zeynep Usta, Minoru Tanaka, Mikihiko Kogo, Susumu Tanaka, Hiroshi Fukuhara, Tomoki Todo   +11 more
wiley   +1 more source

Image‐Based Spatio‐Temporal Interpolation for Split Rendering

Computer Graphics Forum, EarlyView.
Abstract Low‐powered devices – such as small form factor head‐mounted displays (HMDs) – struggle to deliver a smooth and high‐quality viewing experience, due to their limited power and rendering capabilities. Cloud rendering attempts to solve the quality issue, but leads to prohibitive latency and bandwidth requirements, hindering use with HMDs over ...
M. Steiner, T. Köhler, L. Radl, B. Budge, M. Steinberger   +4 more
wiley   +1 more source

GRWD1 enhances HSV-1 replication by facilitating nuclear egress. [PDF]

Microbiol Spectr
Kong Z, Gao C, Liu X, Xue T, Liang X, Yan P, Zhang R, Tang J.   +7 more
europepmc   +1 more source

Edge‐preserving noise for diffusion models

Computer Graphics Forum, EarlyView.
Abstract Classical diffusion models typically rely on isotropic Gaussian noise, treating all regions uniformly and overlooking structural information important for high‐quality generation. We introduce an edge‐preserving diffusion process that generalizes isotropic models via a hybrid noise scheme with an edge‐aware scheduler that smoothly transitions ...
Jente Vandersanden, Sascha Holl, Xingchang Huang, Gurprit Singh   +3 more
wiley   +1 more source

Neuroinflammation and Senescence Are Detected in Brainstems of Mice Latently Infected with HSV-1. [PDF]

Pathogens
Whitmore MA, Harrison KS, Sadeghi H, Plakkot B, Venugopal U, Turtle C, Subramanian M, Jones C.   +7 more
europepmc   +1 more source

Eccrine Squamous Syringometaplasia Mimicking Acute Cutaneous GVHD in a Pediatric HSCT Recipient: Case Report and Brief Review of the Indexed Literature

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Eccrine squamous syringometaplasia (ESS) is an uncommon reactive alteration of eccrine ducts, most often reported in oncologic and transplant settings, where it may clinically mimic acute cutaneous graft‐versus‐host disease (GVHD). We describe a 3‐year‐old boy with chronic granulomatous disease who developed a diffuse erythematous eruption 6 ...
Benedetta Galli, Cecilia Catapano, Iacopo Ghini, Mariateresa Rossi, Marina Venturini, Valeria Boccaletti   +5 more
wiley   +1 more source

Systematic evaluation of HSV-1 Δ34.5Δ47 as a dual-function platform for attenuated HSV-1 vaccine and heterologous antigen delivery. [PDF]

Virol Sin
Wen Z, Wang H, Liao Y, Li S, Shi M, Cui M, Qian J, Sun C.   +7 more
europepmc   +1 more source

Comparison of UL10 gene sequences between HSV-1-WT and HSV-1-ΔUL10.

Comparison of UL10 gene sequences between HSV-1-WT and HSV-1-ΔUL10.
Boli Hu (750407), Changjiang Weng (8127537), Longfeng Zhang (9180148), Yan-Dong Tang (7520780), Li Huang (107408), Qiongqiong Zhou (92521), Chunfu Zheng (286554), Deshi Shi (2266351)   +7 more
core   +1 more source

Structural insights into HSV-1 origin unwinding by the viral proteins UL9 and ICP8. [PDF]

Nucleic Acids Res
Baranovskiy AG, Morstadt LM, Romero EE, Babayeva ND, Tahirov TH.   +4 more
europepmc   +1 more source

Regional Standardization of CLL Management: Results of a Delphi Consensus Process

European Journal of Haematology, EarlyView.
ABSTRACT The therapeutic landscape of chronic lymphocytic leukemia (CLL) has been profoundly transformed by the introduction of Bruton tyrosine kinase and BCL‐2 inhibitors. Despite improved survival outcomes, treatment selection remains complex, particularly in older patients with comorbidities, frailty, and increased infectious vulnerability.
Enrica Antonia Martino, Annalisa Chiarenza, Salvatrice Mancuso, Marco Rossi, Caterina Stelitano, Ignazio Abbene, Sergio Cabibbo, Daniele Caracciolo, Emilia Cotzia, Amalia Figuera, Antonino Greco, Vanessa Innao, Luciano Levato, Carla Marino, Giuseppe Mineo, Laura Nocilli, Giuseppa Penna, Marika Porrazzo, Giorgio Tona, Ernesto Vigna, Fortunato Morabito, Daniela D'Angela, Massimo Gentile   +22 more
wiley   +1 more source