Results 181 to 190 of about 29,786,765 (312)

Partial or complete blocking of gD binding to HVEM affects primary and latent HSV-1 infection as well as eye disease in HSV-1 infected mice. [PDF]

PLoS Pathog
Arya D, Jaggi U, Oh JJ, Wang S, Ghiasi H.   +4 more
europepmc   +1 more source

Significance of Systemic Immune‐Inflammation and Inflammatory Response Indices in Vestibular Neuritis

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction This study investigated the relationship between vestibular neuritis and various systemic inflammatory indices—namely, neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR), monocyte‐to‐lymphocyte ratio (MLR), systemic immune‐inflammation index (SII), and systemic inflammation response index (SIRI) and the ...
Tuğba Tulacı, Mustafa Utku Akbaş, Hasan Çanakçı, Tarık Yetişir, Kamil Gökçe Tulacı, Haşmet Yazıcı, Gulendam Kayıkçı, Omer Hizli   +7 more
wiley   +1 more source

Syncytium-forming HSV-1 in cancer gene therapy: From molecular mechanisms to clinical translation. [PDF]

Virulence
Zhao X, Zhang H, Xu S, Mei L, Feng Z, Wang D, Huang W, Shen Y.   +7 more
europepmc   +1 more source

HSV-1 and VZV co-reactivation: implications for worsening neurological and neurodegenerative diseases. [PDF]

J Neurovirol
Niemeyer CS, Nagel MA, Restrepo D, Bubak AN.   +3 more
europepmc   +1 more source

The impact of frailty on glycaemic control in older adults with type 1 diabetes: An observational study

Diabetic Medicine, EarlyView.
Abstract Aims The type 1 diabetes population is ageing. Frailty is the age‐related physiological decline that occurs across organ systems, increasing the body's vulnerability to stressors. Current consensus‐based guidelines, derived from evidence in type 2 diabetes, prioritise hypoglycaemia avoidance, which increases falls, hospitalisation and ...
Jonathan A. Golding, Scarlett O. Long, Suzy V. Hope, Juliet E. Wright, Ali J. Chakera, Tom J. Levett   +5 more
wiley   +1 more source

GRWD1 enhances HSV-1 replication by facilitating nuclear egress. [PDF]

Microbiol Spectr
Kong Z, Gao C, Liu X, Xue T, Liang X, Yan P, Zhang R, Tang J.   +7 more
europepmc   +1 more source

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

The FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah, Grace Filbertine, Lucy Gill, Asangaedem Akpan, Marie M. Phelan, Helen Louise Wright   +5 more
wiley   +1 more source

Correction: Genetic mutations in HSV-1 replication-defective vectors: Implications for their safety in gene therapy applications. [PDF]

Gene Ther
Cattaneo S, Bettegazzi B, Ingusci S, Verlengia G, Tascini AS, Zucchini S, Codazzi F, Morelli MJ, Marzulli M, Glorioso JC, Simonato M.   +10 more
europepmc   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Systematic evaluation of HSV-1 Δ34.5Δ47 as a dual-function platform for attenuated HSV-1 vaccine and heterologous antigen delivery. [PDF]

Virol Sin
Wen Z, Wang H, Liao Y, Li S, Shi M, Cui M, Qian J, Sun C.   +7 more
europepmc   +1 more source