Results 241 to 250 of about 112,416,099 (307)

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

The Influence of the AgNPs Ligand on the Antiviral Activity Against HSV-2. [PDF]

Int J Nanomedicine
Tomaszewska E, Bednarczyk K, Janicka M, Chodkowski M, Krzyzowska M, Celichowski G, Grobelny J, Ranoszek-Soliwoda K.   +7 more
europepmc   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, Volume 13, Issue 62, 9 November 2026.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

Early second trimester herpes simplex virus type 2 (HSV-2) infection detection in an 18-week fetus: A case report. [PDF]

Radiol Case Rep
Saboor MB, Gerami R.
europepmc   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, Volume 4, Issue 4, Page 419-434, November 2026.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Antiviral Activity of Morus nigra L. Molasses and an Anthocyanin‐Rich Extract Against Herpes Simplex Virus and Development of a Film Formulation

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Quantitative standardization of Morus nigra L. fruit extract and molasses reveals significant total phenolic and anthocyanin contents. Polymer‐based film formulations incorporating these standardized preparations exhibit robust antioxidant capacity and pronounced antiviral efficacy against HSV‐1 and HSV‐2, offering a promising, biocompatible topical ...
Nuraniye Eruygur, Tuğsen Buyukyildirim, Sema Arisoy, Sercan Palanci   +3 more
wiley   +1 more source

IL-12-armed oncolytic HSV-2 enhances CAR T cell efficacy against pancreatic cancer in xenografted models. [PDF]

Front Immunol
Xu C, Wu J, Liu W, Zhou X, Liang Q, Li G, Wang Y, Liu Y, Cai Q, Tang Z, Tu C, Hu H, Liu B, Meng S.   +13 more
europepmc   +1 more source

Diagnostic and Therapeutic Insights From a Case Series of Melkersson‐Rosenthal Syndrome With a Complete Clinical Triad: Unmasking the Overlooked Syndrome

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Recurrent facial nerve palsy, particularly when alternating sides and accompanied by orofacial edema, should raise suspicion for Melkersson–Rosenthal syndrome. Recognition of fissured tongue as part of the clinical triad may facilitate timely diagnosis, avoid unnecessary investigations, and enable appropriate corticosteroid treatment.
Zoran Dudvarski, Katarina Jovanović, Saša Jakovljević, Nemanja Radivojević, Ana Dimitrijević, Konstantin Arsović, Masa Petrovic   +6 more
wiley   +1 more source

Syndemic Synergy of HPV, HIV, and HSV-2 for Oncogenic HPV Replication in Female Sex Workers. [PDF]

Trop Med Infect Dis
Muwonga Tukisadila J, Mboumba Bouassa RS, Tonen-Wolyec S, Loemba H, Muwonga J, Belec L.   +5 more
europepmc   +1 more source