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G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo. [PDF]
Rahman N +4 more
europepmc +1 more source
High prevalence and incidence of HSV-2 among people who inject drugs in Hai Phong, Vietnam, and risk factors associated with seroconversion. [PDF]
D'Ottavi M +18 more
europepmc +1 more source
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Development of a microneutralization assay for HSV-2
Journal of Virological Methods, 2021Plaque Reduction Neutralization Test (PRNT) is the standard assay used for measuring neutralizing antibody responses to Herpes simplex virus type-2 (HSV-2). The PRNT is a cumbersome, time-consuming and laborious assay. The development of a faster, high throughput microneutralization assay (MNA) for HSV-2 viruses carried out in a 96-well format will ...
Melanie S. Horton +12 more
openaire +2 more sources
Antiviral Research, 2004
A number of important risk factors for the acquisition of HSV-2 have been established including female gender, black or Hispanic ethnic origin, HIV infection, age, and increased number of sexual partners. Transmission is influenced by a number of biological factors such as sexual behavior, use of condoms, duration of relationships, and knowledge of a ...
S L, Sacks +10 more
openaire +2 more sources
A number of important risk factors for the acquisition of HSV-2 have been established including female gender, black or Hispanic ethnic origin, HIV infection, age, and increased number of sexual partners. Transmission is influenced by a number of biological factors such as sexual behavior, use of condoms, duration of relationships, and knowledge of a ...
S L, Sacks +10 more
openaire +2 more sources
Modeling the synergy between HSV-2 and HIV and potential impact of HSV-2 therapy
Mathematical Biosciences, 2013Mounting evidence indicates that genital HSV-2 infection may increase susceptibility to HIV infection and that co-infection may increase infectiousness. Accordingly, antiviral treatment of people with HSV-2 may mitigate the incidence of HIV in populations where both pathogens occur. To better understand the epidemiological synergy between HIV and HSV-2,
Feng, Zhilan +4 more
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Acta Microbiologica et Immunologica Hungarica, 2008
Herpes simplex virus type 2 infection is a quite common but frequently asymptomatic, therefore undiagnosed condition. Genital HSV-2 infection may cause neonatal herpes, enhances HIV transmission and may play a role in infertility. To evaluate the prevalence of HSV-2 in Hungary we tested 2500 serum samples for the presence of anti-HSV-2 IgG by ELISA ...
Hettmann, Andrea +4 more
openaire +3 more sources
Herpes simplex virus type 2 infection is a quite common but frequently asymptomatic, therefore undiagnosed condition. Genital HSV-2 infection may cause neonatal herpes, enhances HIV transmission and may play a role in infertility. To evaluate the prevalence of HSV-2 in Hungary we tested 2500 serum samples for the presence of anti-HSV-2 IgG by ELISA ...
Hettmann, Andrea +4 more
openaire +3 more sources
Psychosocial Impact of a Positive HSV‐2 Diagnosis on Adults with Unrecognized HSV‐2 Infection
Public Health Nursing, 2011ABSTRACT Objective: To evaluate the current research on the psychosocial impact of a positive herpes simplex virus type 2 (HSV‐2) diagnosis on asymptomatic adults.Design and Sample: A structured review of PubMed, CINAHL, and MEDLINE resulted in 8 articles published between 2000 and 2008.Measures: Articles were included if they investigated ...
Allison, Provenzale +4 more
openaire +2 more sources
Vaccine, 2011
HSV-2, the primary causative agent of genital herpes, establishes latency in sensory ganglia and reactivates causing recurrent lesions and viral shedding. Induction or expansion of CD4(+) and CD8(+) T cell responses are expected to be important for a successful therapeutic vaccine against HSV-2.
Anna, Wald +9 more
openaire +2 more sources
HSV-2, the primary causative agent of genital herpes, establishes latency in sensory ganglia and reactivates causing recurrent lesions and viral shedding. Induction or expansion of CD4(+) and CD8(+) T cell responses are expected to be important for a successful therapeutic vaccine against HSV-2.
Anna, Wald +9 more
openaire +2 more sources

