Results 71 to 80 of about 112,416,099 (307)

A live-attenuated HSV-2 ICP0 virus elicits 10 to 100 times greater protection against genital herpes than a glycoprotein D subunit vaccine. [PDF]

PLoS ONE, 2011
Glycoprotein D (gD-2) is the entry receptor of herpes simplex virus 2 (HSV-2), and is the immunogen in the pharmaceutical industry's lead HSV-2 vaccine candidate.
William P Halford, Ringo Püschel, Edward Gershburg, Andrew Wilber, Svetlana Gershburg, Brandon Rakowski   +5 more
doaj   +1 more source

The innate immune response to HSV-1: glycoprotein mediated activation of dendritic cells [PDF]

, 2009
Herpes Simplex Virus (HSV) – 1 also known as Human Herpes Virus (HHV) – 1 is a common infectious agent of humans which can cause a wide variety of clinical outcomes, ranging from mild mucocutaneous lesions to long term morbidity and possible mortality.
Reske, A., Reske, A
core  

HSV-2 PLNP LFA receiver operating characteristic (ROC) curves.

, 2019
Each panel member was tested and analyzed in replicate (n = 2), by SeraCare, Inc, using HerpeSelect 2 ELISA from Focus Diagnostics, and the resulting absorbance mean was normalized to generate signal-to-cutoff ratios (reactivity ratios).
Katerina Kourentzi (415276), Andrew S. Paterson (8107757), Heather J. Goux (5507663), Claudia Pedroza (2820298), Alexander Kirkpatrick (8107760), Richard C. Willson (233089), Van Thi Thanh Truong (8107769), Blane Townsend (8107763), Binh V. Vu (293857), Miles Lee (8107766), João R. C. Trabuco (4744053), Balakrishnan Raja (1334814)   +11 more
core   +1 more source

The epidemiology of HIV and HSV-2 infections among women participating in microbicide and vaccine feasibility studies in Northern Tanzania. [PDF]

, 2013
OBJECTIVES: To prepare for future HIV prevention trials, we conducted prospective cohort studies among women working in food and recreational facilities in northern Tanzania.
Watson-Jones Deborah, Joseph Chilongani, Mongi Aika, Watson-Jones, Deborah, John Changalucha (243873), Hashim, Ramadhan, Tony Ao (434475), Hayes Richard, Saidi H. Kapiga (124370), Saidi H Kapiga, Aika Mongi, Aura Andreasen, Deborah Watson-Jones, Aika Mongi (434477), Kathy Baisley (132119), Ramadhan Hashim (148699), Deborah Watson-Jones (230055), Chilongani Joseph, Baisley, Kathy, Francis, Suzanna, Changalucha John, Fiona M. Ewings (309182), Hayes, Richard, Richard Hayes, Chilongani, Joseph, Kathy Baisley, Suzanna Francis, Richard Hayes (32740), Changalucha, John, Aura Andreasen (247728), Joseph Chilongani (434476), Kapiga, Saidi H, Ao, Tony, Mongi, Aika, Andreasen, Aura, Ramadhan Hashim, Andreasen Aura, John Changalucha, Hashim Ramadhan, Francis Suzanna, Ao Tony, Tony Ao, Baisley Kathy, Fiona M Ewings, Ewings Fiona M., Suzanna Francis (434478), Kapiga Saidi H., Ewings, Fiona M   +47 more
core   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Anti-HSV-1 gRNAs impair HSV-1 replication.

, 2016
a) Vero cells were transduced with the indicated gRNAs and subsequently infected with HSV-1-eGFP at an MOI of 0.05. To assess the percentage of virus-infected cells, eGFP-expression was analyzed by flow cytometry at 2 dpi.
Anita C. Schürch (173257), Saskia M. Imhof (2863670), Emmanuel J. H. J. Wiertz (124100), Ferdy R. van Diemen (2863673), Elisabeth M. Kruse (2863667), Robert Jan Lebbink (341442), Marjolein J. G. Hooykaas (2863664), Carlijn E. Bruggeling (2863676), Monique Nijhuis (89548), Petra M. van Ham (214475)   +9 more
core   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Extensive Atypical HSV-2 Ulceration of the Finger

Acta Médica Portuguesa, 2017
N/A.
Nélia Cunha, Pedro Simões, Vasco Serrão   +2 more
openaire   +5 more sources

HSV-2 infection dynamics from multiple model simulations.

, 2018
(A) Total quantity of HSV-2 within the simulation region at all time points throughout year long simulations. (B) Total percentage of tissue damage within the simulation region at all time points throughout year long simulations.
Catherine M. Byrne (5147228), Daniel Coombs (220678), Soren Gantt (632933)   +2 more
core   +1 more source