Results 31 to 40 of about 117,409 (314)
Correlates of HIV-1 genital shedding in Tanzanian women. [PDF]
, 2011 BACKGROUND: Understanding the correlates of HIV shedding is important to inform strategies to reduce HIV infectiousness. We examined correlates of genital HIV-1 RNA in women who were seropositive for both herpes simplex virus (HSV)-2 and HIV-1 and who ...
Clare Tanton +35 more
core +1 more source
Anti-HSV-1 gRNAs impair HSV-1 replication.
, 2016 a) Vero cells were transduced with the indicated gRNAs and subsequently infected with HSV-1-eGFP at an MOI of 0.05. To assess the percentage of virus-infected cells, eGFP-expression was analyzed by flow cytometry at 2 dpi.
Anita C. Schürch (173257) +9 more
core +1 more source
, 2021 Natural products are an excellent source of skeletons for medicinal seeds. Triterpenes and saponins are representative natural products that exhibit anti-herpes simplex virus type 1 (HSV-1) activity.
Keiko Ogawa (1796347) +5 more
core +1 more source
Worldwide circulation of HSV-2 × HSV-1 recombinant strains [PDF]
Scientific Reports, 2017 AbstractHomo sapiens harbor two distinct, medically significant species of simplexviruses, herpes simplex virus (HSV)-1 and HSV-2, with estimated divergence 6–8 million years ago (MYA). Unexpectedly, we found that circulating HSV-2 strains can contain HSV-1 DNA segments in three distinct genes.
David M. Koelle +16 more
openaire +2 more sources
Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
Advanced Healthcare Materials, EarlyView.LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
Chronic inflammation evoked by pathogenic stimulus during carcinogenesis
4 open, 2019 A pathogenic (biological or chemical) stimulus is the earliest information received by a cell that can result in the disruption of homeostasis with consequent development of disease.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj +1 more source
The innate immune response to HSV-1: glycoprotein mediated activation of dendritic cells [PDF]
, 2009 Herpes Simplex Virus (HSV) – 1 also known as Human Herpes Virus (HHV) – 1 is a common infectious agent of humans which can cause a wide variety of clinical outcomes, ranging from mild mucocutaneous lesions to long term morbidity and possible mortality.
Reske, A., Reske, A
core
HSV-2 shedding before and after immunisation.
, 2019 HSV-2 shedding rates were assessed over 45-day swabbing periods before immunisation, after immunisation and after booster immunisation. (A) The number of days with HSV-2 detected was normalized per year. Shown are mean values with 95% CI.
Julie L. Dutton (8138424) +11 more
core +1 more source
Regulation of HSV Transcription.
Journal of Investigative Dermatology, 1984 Herpes simplex virus (HSV) transcripts share many features with both cellular mRNA and the mRNAs expressed by other nuclear-replicating DNA viruses: they are capped, polyadenylated, and generally have an approximately 150 base leader between the cap and translation initiation codon.
openaire +2 more sources
Advanced Materials, EarlyView.We show that sol‐gel‐fractured indium–magnesium oxide combines deep‐ultraviolet responsivity, high carrier mobility, and an excellent memory dynamic range. This unique materials platform enables deep‐ultraviolet long‐afterglow light‐emitting devices with multifunctional integration.
Zhongshi Ju +9 more
wiley +1 more source