Results 11 to 20 of about 120,788 (312)

Worldwide circulation of HSV-2 × HSV-1 recombinant strains [PDF]

Scientific Reports, 2017
AbstractHomo sapiens harbor two distinct, medically significant species of simplexviruses, herpes simplex virus (HSV)-1 and HSV-2, with estimated divergence 6–8 million years ago (MYA). Unexpectedly, we found that circulating HSV-2 strains can contain HSV-1 DNA segments in three distinct genes.
David M. Koelle, Peter Norberg, Matthew P. Fitzgibbon, Ronnie M. Russell, Alex L. Greninger, Meei-Li Huang, Larry Stensland, Lichen Jing, Amalia S. Magaret, Kurt Diem, Stacy Selke, Hong Xie, Connie Celum, Jairam R. Lingappa, Keith R. Jerome, Anna Wald, Christine Johnston   +16 more
openaire   +3 more sources

Effect of genital herpes on cervicovaginal HIV shedding in women co-infected with HIV AND HSV-2 in Tanzania. [PDF]

, 2013
To compare the presence and quantity of cervicovaginal HIV among HIV seropositive women with clinical herpes, subclinical HSV-2 infection and without HSV-2 infection respectively; to evaluate the association between cervicovaginal HIV and HSV shedding ...
Riedner, Gabriele, Leonard Maboko, Mabey, David, Lyamuya Eligius, Helen A Weiss, See Profile, Belec Laurent, Hoelscher Michael, Mabey David, Weiss Helen A., Mary Rusizoka, Lyamuya, Eligius, Helen A. Weiss, Maboko Leonard, Maboko, Leonard, Rusizoka, Mary, Rusizoka Mary, Jim Todd, Belec, Laurent, Todd Jim, Weiss, Helen A, Hayes Richard, Hoelscher, Michael, Laurent Belec, Michael Hoelscher, Todd, Jim, Weiss, Helen A., Hayes, Richard, Richard Hayes, Gabriele Riedner, Riedner Gabriele, Eligius Lyamuya, David Mabey   +32 more
core   +1 more source

HSV-2 parameter values and assumptions.

, 2022
HSV-2 parameter values and assumptions.
Christine Johnston (375038), Laith J. Abu-Raddad (9262524), Sachin Silva (3523043), Houssein H. Ayoub (9262512), Rifat Atun (109572)   +4 more
core   +1 more source

Seroepidemiological study of herpes simplex virus types 1 and 2 in Brazil, Estonia, India, Morocco, and Sri Lanka [PDF]

, 2003
Background: The association between herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus (HIV) and the development of HSV vaccines have increased interest in the study of HSV epidemiology.Objectives: To estimate the age and sex specific ...
Rbai, M, Robinson, NJ, de Oliveira, S Artimos, Gopal, R, Nygard-Kibur, M, Alami, K, Cowan, FM, Uuskula, A, Brown, DW, Mayaud, P, Sridharan, G, El Aouad, R, Ramalingam, S, de Oliveira, SA, Sunil-Chandra, NP, Faillace, T, French, RS   +16 more
core   +1 more source

A subset of human plasmacytoid dendritic cells expresses CD8α upon exposure to herpes simplex virus type 1

Frontiers in Microbiology, 2015
Classical and plasmacytoid dendritic cells (DC) play important roles in the defense against murine and human infections with herpes simplex virus (HSV). So far, CD8α expression has only been reported for murine DC.
Philipp eSchuster, Philipp eSchuster, Sabrina eThomann, Maren eWerner, Jörg eVollmer, Schmidt eBarbara, Schmidt eBarbara   +6 more
doaj   +1 more source

Enhanced Single Image Dehazing Technique based on HSV Color Space

UHD Journal of Science and Technology, 2022
The clarity of images degrades significantly due to the impact of weather conditions such as fog and haze. Persistent particles scatter light, attenuating reflected light from the scene, and the dispersed atmospheric light will mix with the light ...
Mohammed Khalid Othman, Alan Anwer Abdulla   +1 more
doaj   +1 more source

Pediatric glioma stem cells: biologic strategies for oncolytic HSV virotherapy

Frontiers in Oncology, 2013
While glioblastoma multiforme (GBM) is the most common adult malignant brain tumor, GBMs in childhood represent less than 10% of pediatric malignant brain tumors and are phenotypically and molecularly distinct from adult GBMs.
Gregory K Friedman, Joel eRaborn, Virginia M Kelly, Kevin A Cassady, James M Markert, George Yancey Gillespie   +5 more
doaj   +1 more source

De Novo synthesis of VP16 coordinates the exit from HSV latency in vivo [PDF]

, 2009
The mechanism controlling the exit from herpes simplex virus latency (HSV) is of central importance to recurrent disease and transmission of infection, yet interactions between host and viral functions that govern this process remain unclear. The cascade
Sawtell, N.M., Thompson, R.L., Richard L Thompson, Chris M Preston, Nancy M Sawtell, Preston, C.M.   +5 more
core   +1 more source

HSV-1 infection upregulates PAD expression in human fibroblasts.

, 2023
(A) mRNA expression levels of PADI isoforms by RT-qPCR of HSV-1-infected (8 and 16 hpi) vs uninfected (mock) HFFs were normalized to the housekeeping gene glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and expressed as mean fold change ± SEM over mock ...
Leonard Barasa (16318086), Greta Bajetto (16446670), Linda Trifirò (17593086), Qiao Yang (1506640), Stefano Raviola (9357518), Marco De Andrea (186201), Valentina Dell’Oste (412420), Bianca Brugo (17593089), Santo Landolfo (186215), Selina Pasquero (16446682), Sen Sudeshna (17593095), Matteo Biolatti (8816771), Gloria Griffante (9357524), Paul R. Thompson (105487), Francesca Gugliesi (412418), Hafeez Haniff (11029576), Camilla Albano (16446679), Davide Lacarbonara (17593092)   +17 more
core   +1 more source

Phosphate-Engineered DNA Reporters Boost CRISPR-Cas12a Trans-Cleavage for Rapid and Sensitive Nucleic Acid Detection. [PDF]

Adv Sci (Weinh)
We uncover dual CRISPR‐Cas12a trans‐cleavage activities: endonucleolytic cleavage and 3′→5′ exonucleolytic trimming of ssDNA reporters. Mechanism‐guided 3′‐phosphate engineering accelerates substrate cleavage while favoring endonucleolytic processing, enabling Phos‐CRISPR, a rapid (20 min), highly sensitive, and specific platform for nucleic acid ...
Yang R, Guo C, Pei M, Zhang J, Guan X, Zhang S, Liu X, Schalper KT, Avery L, LaSala R, Banach D, Liu C.   +11 more
europepmc   +2 more sources