Results 91 to 100 of about 22,246,700 (213)

Perceptions of donor screening—Do I always need to tell the truth?

open access: yesTransfusion Medicine, EarlyView.
Abstract Background The Donor Health Assessment Questionnaire (DHQ) is fundamental to blood safety. We describe attitudes towards truthfulness among first‐time donors who tested positive for transfusion transmissible infections and those who did not.
Sheila F. O'Brien   +2 more
wiley   +1 more source

Strengths, Weaknesses, Opportunities and Threats (SWOT) Analysis of the Implementation of Public Health Policies on HTLV-1 in Brazil

open access: yesFrontiers in Medicine, 2022
Human T lymphotropic virus 1 (HTLV-1) is a public health issue for most countries and imposes important consequences on patients' health and socioeconomic status. Brazil is one of the global leaders of the public health response to these viruses.
Angelica Espinosa Miranda   +7 more
doaj   +1 more source

Adult T‐cell leukemia/lymphoma in French Guiana (1990–2019): Epidemiology, clinical features, and HTLV‐1 genetic diversity in the two main ethnic populations

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1528-1540, 15 March 2026.
What's new? Adult T‐cell leukemia/lymphoma (ATL) is a rare and aggressive malignancy caused by human T‐cell leukemia virus type 1 (HTLV‐1). The authors comprehensively analyzed the epidemiological and clinical features of ATL over a 30‐year period in French Guiana, a region with high HTLV‐1 endemicity and a multiethnic population.
Jill‐Léa Ramassamy   +16 more
wiley   +1 more source

Immunological characteristics of Spanish IDUs infected with HTLV-2 and HIV-1 [PDF]

open access: yesRetrovirology, 2011
Background HTLV-2 infection has been detected in injecting drug users (IDUs) in Spain, who often are coinfected with HCV and HIV-1. It has been reported that HCV infection increases the immune activation of HIV-1-infected patients. Our objective was to analyze how HTLV-2 infection affects T-cell activation and other immunological parameters such as ...
Moreno Santiago   +6 more
openaire   +2 more sources

HIV-1/HTLV Co-Infection: a Survey of Molecular Basis with Clinical Studies [PDF]

open access: yesPatient Safety and Quality Improvement Journal, 2017
Human immunodeficiency virus type-1 (HIV–1) and human T-cell leukemia virus (HIV-1/HTLV) co-infection is a serious health problem worldwide, especially in endemic areas and vulnerable subjects like intravenous drug abusers.
Marzieh Saberi, Ashraf Tavanaii sani
doaj   +1 more source

A Large Mass on the Thigh

open access: yes
JEADV Clinical Practice, EarlyView.
Claudine Howard‐James   +5 more
wiley   +1 more source

Mechanistic role of GNE‐987 targeting BRD4‐HCP5 axis in pediatric T‐cell acute lymphoblastic leukemia

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
Abstract This study aims to explore the mechanism of action of the Bromodomain‐containing protein 4 (BRD4) inhibitor GNE‐987 in the treatment of pediatric T‐cell Acute Lymphoblastic Leukemia (T‐ALL), focusing on its effect in inhibiting T‐ALL cell proliferation by activating the HLA Complex P5 (HCP5) Super‐enhancer.
Xu Sang   +6 more
wiley   +1 more source

Regulation of AP-1 activity by the HTLV-2 APH-2 protein [PDF]

open access: yesRetrovirology, 2011
In contrast to HTLV-1 which causes adult T-cell leukemia/lymphoma (ATL/ATLL) and HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), the role of HTLV-2 in human disease is less clearly defined but infection is associated with rare lympho-proliferative and neurological disorders.
Sheehy Noreen   +2 more
openaire   +2 more sources

A Fashi Lymphoproliferative Phenotype Reveals Non-Apoptotic Fas Signaling in HTLV-1-Associated Neuroinflammation [PDF]

open access: yes, 2017
Human T-cell lymphotropic virus (HTLV)-1 was the first human retrovirus to be associated to cancer, namely adult T-cell leukemia (ATL), but its pathogenesis remains enigmatic, since only a minority of infected individuals develops either ATL or the ...
Anne Mieke Vandamme   +18 more
core   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li   +13 more
wiley   +1 more source

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