The reasons to include the serology of human T-lymphotropic virus types 1 and 2 (HTLV-1 and HTLV-2) in the clinical follow-up of patients with viral hepatitis B and C in Brazil. [PDF]
PLoS Neglected Tropical Diseases, 2020 BACKGROUND:The WHO established targets for 2030 to globally reduce new viral hepatitis B and C infections by 90% and deaths by 65% and recommends searching for coinfections that increase the progression of chronic liver infections towards cirrhosis and ...
Karoline Rodrigues Campos +5 more
doaj +3 more sources
Neurological Aspects of HIV-1/HTLV-1 and HIV-1/HTLV-2 Coinfection. [PDF]
Pathogens, 2020 Simultaneous infection by human immunodeficiency viruses (HIV) and human T-lymphotropic viruses (HTLV) are not uncommon since they have similar means of transmission and are simultaneously endemic in many populations. Besides causing severe immune dysfunction, these viruses are neuropathogenic and can cause neurological diseases through direct and ...
Araujo AQ.
europepmc +7 more sources
Silencers of HTLV-1 and HTLV-2: the pX-encoded latency-maintenance factors. [PDF]
Retrovirology, 2019 Of the members of the primate T cell lymphotropic virus (PTLV) family, only the human T-cell leukemia virus type-1 (HTLV-1) causes disease in humans-as the etiological agent of adult T-cell leukemia/lymphoma (ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other auto-inflammatory disorders.
Harrod R.
europepmc +6 more sources
Seroprevalence of HTLV-1 and HTLV-2 amongst mothers and children in Malawi within the context of a systematic review and meta-analysis of HTLV seroprevalence in Africa [PDF]
Tropical medicine & international health, 2016 OBJECTIVES: Human T‐lymphotropic virus (HTLV)‐1 causes T‐cell leukaemia and myelopathy. Together with HTLV‐2, it is endemic in some African nations. Seroprevalence data from Malawi are scarce, with no reports on associated disease incidence.
Bland, M +7 more
core +2 more sources
HTLV-1 and HTLV-2: highly similar viruses with distinct oncogenic properties [PDF]
Frontiers in Microbiology, 2014 HTLV-1 and HTLV-2 share broad similarities in their overall genetic organization and expression pattern, but they differ substantially in their pathogenic properties. This review outlines distinctive features of HTLV-1 and HTLV-2 that might provide clues to explain their distinct clinical outcomes.
CIMINALE, VINCENZO +3 more
openaire +4 more sources
Estimating the number of HTLV-2 infected persons in the world [PDF]
Retrovirology, 2015 The number of HTLV-1 infected persons in the world has recently been estimated to be at least at 5 to 10 million or perhaps higher due to unavailable data (Gessain and Cassar Front Microbiol 2012). We decided to undertake a similar estimation for HTLV-2 infection. A targeted review of the literature revealed HTLV-2 prevalence estimates in blood donors (
Murphy, Edward L +2 more
openaire +2 more sources
Fine tuning of the temporal expression of HTLV-1 and HTLV-2 [PDF]
Frontiers in Microbiology, 2013 Human T-cell leukemia virus types 1 and 2 (HTLV-1 and HTLV-2) are delta retroviruses that share a common overall genetic organization, splicing pattern, and ability to infect and immortalize T-cells in vitro. However, HTLV-1 and HTLV-2 exhibit a clearly distinct pathogenic potential in infected patients. To find clues to the possible viral determinants
Ilaria eCavallari +6 more
openaire +5 more sources
HTLV-1, HTLV-2, and associated diseases
Oxford Textbook of Medicine, 2010 Abstract Human T-cell leukaemia virus (HTLV)-1 and HTLV-2 belong to the genus Deltaretrovirus of the family Retroviridae. They only infect humans, produce a lifelong infection, and can be transmitted from mother to child, through sexual intercourse, and via cellular blood components and organ transplantation.
Verdonck, K., Gotuzzo, E.
openaire +4 more sources
Epidemiological analysis of HTLV-1 and HTLV-2 infection among different population in Central China. [PDF]
PLoS ONE, 2013 BACKGROUND: HTLV-1 and HTLV-2 are retroviruses linked etiologically to various human diseases, and both of them can be transmitted by vertical route, sexual intercourse, blood transfusion and intravenous drug use.
Yunyun Ma +9 more
doaj +2 more sources
Modeling HTLV-1 and HTLV-2 co-infection dynamics
AIMS MathematicsWith the increasing prevalence of viral infections, the human T-cell leukemia virus (HTLV) is becoming a focal point of research. Of the four identified strains, HTLV-1 and HTLV-2 are particularly associated with various health issues.
E. A. Almohaimeed +2 more
doaj +2 more sources