Results 41 to 50 of about 33,805 (209)

Multicyclic D‐Stereospecific Hydrolase Dimer With High Sustained Activity

Angewandte Chemie, EarlyView.
Protein macrocyclization was applied to a thermally unstable D‐stereospecific hydrolase using in situ cyclization of proteins (INCYPRO). This site‐specific cross‐linking approach enhanced the resistance of the enzyme to heat and cosolvents.
Anissa Haim, Sandra Liebscher, Rasmus Klintrot, Lorenzo Vallino, Marcelo Masman, Andreas H. Simon, Marianne Hahn, Sven Hennig, Saskia Neubacher, Frank Bordusa, Tom N. Grossmann   +10 more
wiley   +2 more sources

Prevalence of human T-lymphotropic virus type 1 and 2 (HTLV-1/-2) infection in pregnant women in Brazil: a systematic review and meta-analysis

Scientific Reports, 2021
Human T-lymphotropic virus type 1 (HTLV-1) infection may cause serious disease, while pathogenicity of HTLV-2 is less certain. There are no screening or surveillance programs for HTLV-1/-2 infection in Brazil.
Bruna Angelo Vieira, Augusto Bacelo Bidinotto, William Jones Dartora, Luana Giongo Pedrotti, Vanessa Martins de Oliveira, Eliana Márcia Wendland   +5 more
doaj   +1 more source

Ancient, independent evolution and distinct molecular features of the novel human T-lymphotropic virus type 4

Retrovirology, 2009
Background Human T-lymphotropic virus type 4 (HTLV-4) is a new deltaretrovirus recently identified in a primate hunter in Cameroon. Limited sequence analysis previously showed that HTLV-4 may be distinct from HTLV-1, HTLV-2, and HTLV-3, and their simian ...
Wolfe Nathan D, Pryor Kendle N, Marriott Susan J, Katzourakis Aris, Gray Rebecca R, Jia Hongwei, Qari Shoukat H, Salemi Marco, Switzer William M, Burke Donald S, Folks Thomas M, Heneine Walid   +11 more
doaj   +1 more source

Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis

Viruses, 2010
Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes both in vitro and in vivo.
Patrick L. Green, Priya Kannian
doaj   +1 more source

Hepatitis C viral load in HCV-monoinfected and HCV/HIV-1-, HCV/HTLV-1/-2-, and HCV/HIV/HTLV-1/-2-co-infected patients from São Paulo, Brazil

Brazilian Journal of Infectious Diseases, 2018
Co-infections of hepatitis C virus (HCV) and either human immunodeficiency virus type 1 (HIV-1), human T-cell lymphotropic virus type 1 (HTLV-1) or type 2 (HTLV-2) have been described as having an impact on HCV viremia and subsequent disease progression.
Fabiana Aparecida Alves, Karoline Rodrigues Campos, Marcílio Figueiredo Lemos, Regina Célia Moreira, Adele Caterino-de-Araujo   +4 more
doaj   +1 more source

HTLV infection in Brazil’s second-largest indigenous reserve

Scientific Reports, 2022
Human T-lymphotropic viruses 1 and 2 (HTLV-1/2) have a worldwide distribution. HTLV-1 has been associated with several diseases, including an aggressive malignant disease known as adult T-cell leukemia/lymphoma and a chronic inflammatory neurological ...
Carolina Amianti, Larissa Melo Bandeira, Gabriela Alves Cesar, Sabrina Weis-Torres, Tayana Serpa Ortiz Tanaka, Indianara Ramires Machado, Crhistinne Cavalheiro Maymone Gonçalves, Simone Simionatto, Erica Cristina dos Santos Schnaufer, Felipe Bonfim Freitas, Antonio Carlos Rosário Vallinoto, Julio Croda, Ana Rita Coimbra Motta-Castro   +12 more
doaj   +1 more source

Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects

Viruses, 2016
Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of ...
Benjamin Usadi, Roberta Bruhn, Jue Lin, Tzong-Hae Lee, Elizabeth Blackburn, Edward L. Murphy   +5 more
doaj   +1 more source

Loop-Mediated Isothermal Amplification (LAMP) Assay for Rapid and Accurate Confirmatory Diagnosis of HTLV-1/2 Infection

Viruses, 2020
Laboratory diagnosis of human T-lymphotropic viruses (HTLV) 1 and 2 infection is performed by serological screening and further confirmation with serological or molecular assays.
Yago Gomes, Adele Caterino-de-Araujo, Karoline Campos, Maria Gisele Gonçalves, Ana Claudia Leite, Marco Antonio Lima, Abelardo Araújo, Marcus Tulius Silva, Otávio Espíndola   +8 more
doaj   +1 more source

Clinical characteristics and outcomes of infection with human T-lymphotropic virus in a non-endemic area: a single institution study

Frontiers in Microbiology, 2023
IntroductionUnderstanding of human T-lymphotropic virus (HTLV) remains largely based on epidemiologic and clinical data from endemic areas. Globalization has resulted in migration of persons living with HTLV (PLHTLV) from endemic to non-endemic areas ...
Margery Gang, Feng Gao, Sneha Poondru, Theodore Thomas, Lee Ratner   +4 more
doaj   +1 more source

HIGHLIGHTS ON DISTINCTIVE STRUCTURAL AND FUNCTIONAL PROPERTIES OF HTLV TAX PROTEINS.

Frontiers in Microbiology, 2013
Human T-cell Leukemia Viruses (HTLVs) are complex human retroviruses of the Deltaretrovirus genus. Four types have been identified thus far, with HTLV-1 and HTLV-2 much more prevalent than HTLV-3 or -4 .
Maria Grazia Romanelli, Erica eDiani, Elisa eBergamo, Claudio eCasoli, Vincenzo eCiminale, Françoise eBex, Umberto eBertazzoni   +6 more
doaj   +1 more source