Results 71 to 80 of about 33,805 (209)

Modeling HTLV-1 and HTLV-2 co-infection dynamics

open access: yesAIMS Mathematics
With the increasing prevalence of viral infections, the human T-cell leukemia virus (HTLV) is becoming a focal point of research. Of the four identified strains, HTLV-1 and HTLV-2 are particularly associated with various health issues. Both strains exhibit similar biological characteristics and transmission pathways, making them prevalent in specific ...
E. A. Almohaimeed   +2 more
openaire   +2 more sources

Immunological characteristics of Spanish IDUs infected with HTLV-2 and HIV-1 [PDF]

open access: yesRetrovirology, 2011
Background HTLV-2 infection has been detected in injecting drug users (IDUs) in Spain, who often are coinfected with HCV and HIV-1. It has been reported that HCV infection increases the immune activation of HIV-1-infected patients. Our objective was to analyze how HTLV-2 infection affects T-cell activation and other immunological parameters such as ...
Moreno Santiago   +6 more
openaire   +2 more sources

Perceptions of donor screening—Do I always need to tell the truth?

open access: yesTransfusion Medicine, EarlyView.
Abstract Background The Donor Health Assessment Questionnaire (DHQ) is fundamental to blood safety. We describe attitudes towards truthfulness among first‐time donors who tested positive for transfusion transmissible infections and those who did not.
Sheila F. O'Brien   +2 more
wiley   +1 more source

Regulation of AP-1 activity by the HTLV-2 APH-2 protein [PDF]

open access: yesRetrovirology, 2011
In contrast to HTLV-1 which causes adult T-cell leukemia/lymphoma (ATL/ATLL) and HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), the role of HTLV-2 in human disease is less clearly defined but infection is associated with rare lympho-proliferative and neurological disorders.
Sheehy Noreen   +2 more
openaire   +2 more sources

Pathogen‐reduced platelet concentrates in France: Impact on the risk of transfusion‐transmitted infections, 2017–2024

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Pathogen reduction (PR) using amotosalen‐UVA was implemented for 100% of platelet concentrates (PCs) in France in November 2017. No bacterial testing was in place earlier. The impact of PR on the risk of transfusion‐transmitted infections (TTIs) from November 2017 to December 2022 (vs.
Syria Laperche   +11 more
wiley   +1 more source

Re‐entry of donors deferred for false‐reactive screening tests in Canada: 10 years post implementation

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Canadian Blood Services implemented a re‐entry programme in 2014. Donors deferred because of false‐reactive or indeterminate screening tests can provide a specimen for re‐entry testing 6 months after their initial test, and resume donating if they test negative for all infectious markers.
Chinchin Wang   +4 more
wiley   +1 more source

Evaluation of bovine leukaemia virus infection control measures in Japanese Black beef cattle breeding farms: A 7‐year longitudinal study based on proviral load

open access: yesVeterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Bovine leukaemia virus (BLV) infection remains a major problem for Japanese Black (Wagyu) cattle, and effective and sustainable control measures are essential to prevent its spread in breeding herds. This study aimed to monitor the BLV infection status of all cattle at a Japanese Black breeding farm in Kagoshima Prefecture, Japan ...
Makoto Kajisa   +9 more
wiley   +1 more source

Lactate Metabolism‐Immune Regulation‐Related Gene Signature in Lower‐Grade Gliomas: Prognostic Model Development and Immune Characterization

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Lactate metabolism‐immune regulation‐related gene signature (PLA2G2A, TNFRSF12A, VAV3) predicts glioma prognosis. PLA2G2A promotes ECM remodeling, tumor‐associated inflammation, and EMT, leading to enhanced proliferation, invasion, and unfavorable outcomes.
Enhao Zhang   +7 more
wiley   +1 more source

Functional comparison of antisense proteins of HTLV-1 and HTLV-2 in viral pathogenesis [PDF]

open access: yesFrontiers in Microbiology, 2013
The production of antisense transcripts from the 3' long terminal repeat (LTR) in human T-lymphotropic retroviruses has now been clearly demonstrated. After the identification of the antisense strand-encoded human T-lymphotropic virus type 1 (HTLV-1) bZIP (HBZ) factor, we reported that HBZ could interact with CRE-binding protein (CREB) transcription ...
Barbeau, Benoit   +2 more
openaire   +4 more sources

Adult T‐cell leukemia/lymphoma in French Guiana (1990–2019): Epidemiology, clinical features, and HTLV‐1 genetic diversity in the two main ethnic populations

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1528-1540, 15 March 2026.
What's new? Adult T‐cell leukemia/lymphoma (ATL) is a rare and aggressive malignancy caused by human T‐cell leukemia virus type 1 (HTLV‐1). The authors comprehensively analyzed the epidemiological and clinical features of ATL over a 30‐year period in French Guiana, a region with high HTLV‐1 endemicity and a multiethnic population.
Jill‐Léa Ramassamy   +16 more
wiley   +1 more source

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