Results 11 to 20 of about 43,354 (271)
Upregulation of Neuropilin-1 Inhibits HTLV-1 Infection
Infection with human T-cell leukemia virus type 1 (HTLV-1) can produce a spectrum of pathological effects ranging from inflammatory disorders to leukemia. In vivo, HTLV-1 predominantly infects CD4+ T-cells.
Wesley Kendle +5 more
doaj +1 more source
HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy [PDF]
The risk of disease associated with persistent virus infections such as HIV-I, hepatitis B and C, and human T-lymphotropic virus-I (HTLV-I) is strongly determined by the virus load.
Bangham, C.R.M. +16 more
core +2 more sources
No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Burmeister, Thomas +4 more
core +1 more source
Human T-lymphotropic virus types I and II (HTLV-I and -II) cause myelopathy; HTLV-I, but not HTLV-II, causes adult T-cell leukemia. Whether HTLV-II is associated with other diseases is unknown.
Edward L. Murphy +10 more
doaj +1 more source
Human T cell leukemia virus type-I (HTLV-I) infection is associated with spontaneous T cell activation and uncontrolled lymphocyte proliferation. An exacerbated type-1 immune response with production of pro-inflammatory cytokines (interferon-gamma and ...
Silvane Braga Santos +4 more
doaj +1 more source
HTLV‐I Uveitis: A Distinct Clinical Entity Caused by HTLV‐I [PDF]
Seroepidemiological, clinical and virological studies were carried out in an HTLV‐I endemic area to find out if HTLV‐I caused an intraocular inflammatory disorder, uveitis. The seroprevalence in patients with uveitis without defined etiologies (62/175, 35.4%) was significantly higher than that in patients with non‐uveitic ocular diseases (42/261, 16.1%)
Mochizuki, Manabu +9 more
openaire +2 more sources
Cholesterol dependence of HTLV-I infection [PDF]
Cholesterol-rich plasma membrane microdomains are important for entry of many viruses, including retro-viruses. Depletion of cholesterol with 2-hydroxypropyl-β-cyclodextrin inhibits entry of human T cell leukemia virus type I (HTLV-1) and HTLV-I envelope
Jones, Kathryn S +4 more
core +2 more sources
DETECTION OF HTLV-I ANTIBODIES AND DNA IN BLOOD SAMPLE OF A PATIENT WITH MYELOPATHY IN NIGERIA
We describe a case of human T-lymphotropic virus type I associated myelopathy in a 50-year old woman in Nigeria. The patient presented with progressive loss of tone to the two lower limbs and later inability to walk.
O. D. OLALEYE +4 more
doaj +1 more source
Prevalence of Human T-Lymphotropic Virus Types I and II in Patients With Hematological Disorders in Isfahan, Iran [PDF]
Background: Human T-cell lymphotropic virus types I and II (HTLV-I and HTLV-II) are deltaretroviruses which may cause leukemia, lymphoma and HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Ghorani, Mohammadreza. +4 more
core +3 more sources
High prevalence of bronchiectasis is linked to HTLV-1-associated inflammatory disease. [PDF]
BACKGROUND: Human T-lymphotropic virus type 1 (HTLV-1), a retrovirus, is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukaemia/lymphoma (ATLL).
A Gessain +37 more
core +1 more source

