Results 61 to 70 of about 21,148,340 (178)
The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo +4 more
wiley +1 more source
The occurrence of HTLV-I/II and HIV-1 coinfections have been shown to be frequent, probably in consequence of their similar modes of transmission. This paper presents the prevalence of coinfection of HTLV among HIV-1 infected and AIDS patients in Belém ...
Vallinoto ACR +7 more
doaj
HTLV-I and HTLV-II are endemic in some areas of Brazil, where an associated disease, HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) have been diagnosed in significant number of infected individuals. Tuberculosis has been demonstrated
Marcio Menna-Barreto, Denise C. Machado
doaj +1 more source
Oral Relapsing Lymphomatoid Papulosis: A Case Report
ABSTRACT Lymphomatoid papulosis (LyP) is a CD30+ T‐cell lymphoproliferative disorder rarely involving mucosa, where it may mimic aggressive lymphomas. This case highlights its chronic relapsing course, diagnostic challenges with ALK‐negative anaplastic T‐cell lymphoma, and the importance of long‐term follow‐up despite a favorable prognosis.
A. Bitton +7 more
wiley +1 more source
We found that SOCS3 deficiency activates STAT3 to enhance glioma stem cell (GSC) stemness and survival. We demonstrated that IL‐6 rescues STAT3 signaling and reverses SOCS3‐mediated tumor suppression. We revealed that SOCS3‐low GSCs exhibit enriched p53 and JAK‐STAT pathway activity. This study provides new mechanistic insights into SOCS3‐STAT3 axis in
Jingtao Wang +5 more
wiley +1 more source
HTLV-1 proviral load of symptomatic patients.
HTLV-1 proviral load of symptomatic patients.
Ariel Fridman (7961834) +11 more
core +1 more source
Prevalence of anti-HTLV-I & anti-HTLV-II antibodies in Blood donors in Bushehr Province
Human T-cll leukemia virus type 1 (HTLV-I) and HTLV-II are type C oncoviruses, members of the family Retroviridae. Blood transfusion is a transmission route. Screening for HTLV is routine in Khorasan Province/Iran.
Mahmood Reza Poukarim +3 more
doaj
While several oncogenic pathogens cause site‐specific cancers, uncertainties remain about many other chronic infections and combined pathogen effects, especially in non‐Western populations. Using a large case–cohort study nested within the China Kadoorie Biobank, the authors found that co‐infection was common, with a mean of 10 pathogens per individual.
Ling Yang +212 more
wiley +1 more source
Relative frequency of Human T-cell Lymphotropic Virus I/II in HIV/AIDS patients
Background: Human T-cell lymphotropic virus HTLV-I/II is a retrovirus that has been associated with different diseases. HTLV-I/II routes of transmissions are exposure to contaminated blood, blood transfusion, needle sharing, breast feeding, and sexual ...
Mohsen Meidani +3 more
doaj +1 more source
Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley +1 more source

