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Antibody profile of early HTLV-I infection

The Lancet, 1990
To define the antibody profile of early seroconversion in infection with human T-cell lymphotropic virus type I (HTLV-I), consecutive serum samples from 10 subjects presumed to have seroconverted on the basis of the particle agglutination test were studied by three enzyme immunoassays and two confirmatory tests (radioimmunoprecipitation and western ...
Y M, Chen   +6 more
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Antibodies to HTLV-I in Japanese Immigrants in Brazil

JAMA: The Journal of the American Medical Association, 1986
To the Editor.— Human T-cell lymphotropic virus type I (HTLV-I), the causative agent of adult T-cell leukemia, is endemic in southern Japan, 1 the Caribbean islands, 2 and parts of Africa. 3 The prevalence of antibodies to HTLV-I is highest in Okinawa, Japan, where up to 31% of adults are seropositive in some regions. 4 Moreover, a high seroprevalence
T, Kitagawa   +4 more
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No antibodies to HTLV-I and HIV in patients with dementia in Finland

Alzheimer Disease & Associated Disorders, 1987
Patients with human immunodeficiency virus (HIV) have often progressive dementia. Human T cell lymphotropic virus Type I (HTLV-I) infection has not been reported to cause dementia. We tested antibodies to HTLV-I and HIV in serum and cerebrospinal fluid in 69 Finnish patients referred because of dementia to an outpatient department of neurology.
R, Sulkava, J, Korpela, T, Erkinjuntti
openaire   +2 more sources

Roles of HTLV-I p19 and Natural Antibody to HTLV-I in Host Immune Responses

1985
Since the discovery of human T cell leukemia/lymphoma virus type I (HTLV-I) [5], the immune status of HTLV-I- infected hosts, including patients with adult T cell leukemia (ATL), has not yet been sufficiently investigated [2–4]. As the first step in this kind of study, we have studied the nonspecific activity of peripheral mononuclear cells (PMNC) from
T, Aoki   +7 more
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Lack of Evidence of HTLV-I Antibodies in the Finnish Population

Scandinavian Journal of Infectious Diseases, 1989
5,287 serum samples from 2 different sources in Finland, people possibly at risk and healthy blood donors, were tested for the presence of HTLV-I antibodies. No positive cases were found. The result suggests that this virus is not endemic in Finland. 10 cases gave repeatedly a low positive value in the enzyme immune assay (EIA) test but were confirmed ...
P, Leinikki   +5 more
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Adult T-Cell Leukemia with Anti-HTLV-I Antibody but No HTLV-I DNA in Tumor Cells

Acta Haematologica, 2001
Adult T-cell leukemia (ATL) is usually defined as a malignant disease of T cells infected by human T-lymphotropic virus type I (HTLV-I). In the present study, we describe a 49-year-old woman with an acute type ATL, whose leukemic cells do not contain the HTLV-I genome. Laboratory tests revealed an increase in abnormal lymphocytes with convoluted nuclei,
H, Fujiwara   +6 more
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Diagnosis of HAM/TSP based on CSF proviral HTLV-I DNA and HTLV-I antibody index

Neurology, 2001
The contribution of human T-cell lymphotropic virus (HTLV-I) DNA by PCR in CSF and the intrathecal synthesis of antibodies to HTLV-I by the antibody index (AI) to the diagnosis of HTLV-1-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) were evaluated. Cases of spastic paraparesis compatible with HAM/TSP had increased AI for HTLV-I (60/73)
M, Puccioni-Sohler   +8 more
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Diversity of intrathecal antibody synthesis against HTLV-I and its relation to HTLV-I associated myelopathy

Journal of Neurology, 1996
The humoral immune response against human T-cell lymphotropic virus type I (HTLV-I) in the central nervous system (CNS) compartment and in the blood was investigated by enzyme immunoassay using 16 synthetic peptides corresponding to HTLV-I core and envelope sequences. We evaluated paired samples of cerebrospinal fluid and serum from HTLV-I seropositive
B, Kitze   +9 more
openaire   +2 more sources

Incidence of antibody to HTLV‐I is not increased in Japanese MS patients

Neurology, 1987
To examine the association between MS and anti-human T-cell lymphotropic virus-I (HTLV-I) antibody, we studied serum and CSF antibody to HTLV-I in 27 Japanese MS patients by an indirect immunofluorescence method sensitive and specific enough to detect carriers of HTLV-I. The antibody was detected in 3 of 27 MS patients (11.1%), in 4 of 48 patients (8.3%
Y, Kuroda   +3 more
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High seroprevalence of anti–HTLV‐I antibody in rheumatoid arthritis

Arthritis & Rheumatism, 1996
AbstractObjective. To investigate the association between human T lymphotropic virus type I (HTLV‐I) infection and rheumatoid arthritis (RA) in Nagasaki, an area highly endemic for HTLV‐I infection.Methods. Sera from 113 female patients with RA and 19,796 female blood donors were screened for anti–HTLV‐I antibodies with a gelatin particle agglutination
K, Eguchi   +5 more
openaire   +2 more sources

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