Results 181 to 190 of about 16,224 (216)

Adult T-Cell Leukemia with Anti-HTLV-I Antibody but No HTLV-I DNA in Tumor Cells

Acta Haematologica, 2001
Adult T-cell leukemia (ATL) is usually defined as a malignant disease of T cells infected by human T-lymphotropic virus type I (HTLV-I). In the present study, we describe a 49-year-old woman with an acute type ATL, whose leukemic cells do not contain the HTLV-I genome. Laboratory tests revealed an increase in abnormal lymphocytes with convoluted nuclei,
H, Fujiwara, N, Arima, T, Matsumoto, H, Ohtsubo, K, Matsushita, T, Kukita, C, Tei   +6 more
openaire   +2 more sources

Tropical Spastic Paraparesis: HTLV-I Antibodies in Patients from the Seychelles

New England Journal of Medicine, 1987
exaly   +2 more sources

Diagnosis of HAM/TSP based on CSF proviral HTLV-I DNA and HTLV-I antibody index

Neurology, 2001
The contribution of human T-cell lymphotropic virus (HTLV-I) DNA by PCR in CSF and the intrathecal synthesis of antibodies to HTLV-I by the antibody index (AI) to the diagnosis of HTLV-1-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) were evaluated. Cases of spastic paraparesis compatible with HAM/TSP had increased AI for HTLV-I (60/73)
M, Puccioni-Sohler, M, Rios, S M, Carvalho, R R, Gonçalves, C, Oliveira, R B, Correa, S, Novis, M S, de Oliveira, C, Bianco   +8 more
openaire   +2 more sources

Diversity of intrathecal antibody synthesis against HTLV-I and its relation to HTLV-I associated myelopathy

Journal of Neurology, 1996
The humoral immune response against human T-cell lymphotropic virus type I (HTLV-I) in the central nervous system (CNS) compartment and in the blood was investigated by enzyme immunoassay using 16 synthetic peptides corresponding to HTLV-I core and envelope sequences. We evaluated paired samples of cerebrospinal fluid and serum from HTLV-I seropositive
B, Kitze, K, Usuku, S, Izumo, M, Nakamura, H, Shiraki, S, Ijichi, S, Yashiki, T, Fujiyoshi, S, Sonoda, M, Osame   +9 more
openaire   +2 more sources

Incidence of antibody to HTLV‐I is not increased in Japanese MS patients

Neurology, 1987
To examine the association between MS and anti-human T-cell lymphotropic virus-I (HTLV-I) antibody, we studied serum and CSF antibody to HTLV-I in 27 Japanese MS patients by an indirect immunofluorescence method sensitive and specific enough to detect carriers of HTLV-I. The antibody was detected in 3 of 27 MS patients (11.1%), in 4 of 48 patients (8.3%
Y, Kuroda, H, Shibasaki, H, Sato, K, Okochi   +3 more
openaire   +2 more sources

HTLV-I-SPECIFIC ANTIBODY IN AIDS PATIENTS AND OTHERS AT RISK

The Lancet, 1984
Serum samples from 440 acquired immunodeficiency syndrome (AIDS) patients or individuals at risk for AIDS were examined by the enzyme-linked immunosorbent assay technique for antibodies to HTLV-I core proteins. Specific antibodies were detected in 7% of AIDS patients, 7% of patients with lymphadenopathy, 0% of healthy homosexual men, and 12% of healthy
Marjorie Robert-Guroff, Bijan Safai, EdwardP. Gelmann, PeterW.A. Mansell, JeromeE. Groopman, GurdipS. Sidhu, AlvinE. Friedman-Kien, AnneC. Bayley, DouglasW. Blayney, Michael Lange, JordanW. Gutterman, JamesL. Goedert, NealH. Steigbigel, JoyceM. Johnson, Robert Downing, RobertC. Gallo   +15 more
openaire   +2 more sources

High seroprevalence of anti–HTLV‐I antibody in rheumatoid arthritis

Arthritis & Rheumatism, 1996
AbstractObjective. To investigate the association between human T lymphotropic virus type I (HTLV‐I) infection and rheumatoid arthritis (RA) in Nagasaki, an area highly endemic for HTLV‐I infection.Methods. Sera from 113 female patients with RA and 19,796 female blood donors were screened for anti–HTLV‐I antibodies with a gelatin particle agglutination
K, Eguchi, T, Origuchi, H, Takashima, K, Iwata, S, Katamine, S, Nagataki   +5 more
openaire   +2 more sources

An inverse correlation of HTLV-I viral load in CSF and intrathecal synthesis of HTLV-I antibodies in TSP/HAM

Neurology, 1999
The authors measured human T-cell lymphotrophic virus type I (HTLV-I) proviral load and intrathecal synthesis of antibodies to HTLV-I in CSF of 13 Brazilian patients with tropical spastic paraparesis/ HTLV-I-associated myelopathy (HAM). The authors also measured HTLV-I proviral load in peripheral blood mononuclear cells of five of these patients and ...
M, Puccioni-Sohler, M, Rios, C, Bianco, S W, Zhu, C, Oliveira, S A, Novis, M S, Pombo-de-Oliveira   +6 more
openaire   +2 more sources

Intrathecal synthesis of IgG antibodies to HTLV-I supports an etiological role for HTLV-I in tropical spastic paraparesis

Annals of Neurology, 1988
High titers of antibody to human T-lymphotropic virus type I (HTLV-I) have been reported in the sera and cerebrospinal fluids of patients with tropical spastic paraparesis. By means of agarose isoelectric focusing and selective immunoblotting, we demonstrated oligoclonal bands of immunoglobulin G antibodies to HTLV-I in the serum and cerebrospinal ...
M, Ceroni, P, Piccardo, P, Rodgers-Johnson, C, Mora, D M, Asher, D C, Gajdusek, C J, Gibbs   +6 more
openaire   +2 more sources

HTLV‐I‐associated myelopathy: Oligoclonal immunoglobulin G bands contain anti‐HTLV‐I p24 antibody

Annals of Neurology, 1988
AbstractHuman T‐cell lymphotropic virus type I (HTLV‐I)‐associated myelopathy (HAM) and tropical spastic paraparesis belong to a new group of neurological diseases associated with retroviral infection. An HTLV‐I‐like virus has recently been implicated in multiple sclerosis as well.
L M, Grimaldi, R P, Roos, S G, Devare, J M, Casey, Y, Maruo, T, Hamada, K, Tashiro   +6 more
openaire   +2 more sources