Results 181 to 190 of about 26,175 (228)

Serum antibodies to HTLV-I in human demyelinating disease

Acta Neurologica Scandinavica, 1987
Serum HTLV-I antibodies were measured in 17 MS patients and 2 closely matched control groups by 2 different independent assays. A highly sensitive particle agglutination test was used to detect HTLV-I core protein antigens and an immunoblot assay with E.
L, Epstein, B, Blumberg, J, Crowley, K, Samuel, J, Goudsmit, S, Cook, P, Dowling   +6 more
openaire   +2 more sources

Roles of HTLV-I p19 and Natural Antibody to HTLV-I in Host Immune Responses

1985
Since the discovery of human T cell leukemia/lymphoma virus type I (HTLV-I) [5], the immune status of HTLV-I- infected hosts, including patients with adult T cell leukemia (ATL), has not yet been sufficiently investigated [2–4]. As the first step in this kind of study, we have studied the nonspecific activity of peripheral mononuclear cells (PMNC) from
T, Aoki, C, Hamada, S, Ohno, H, Miyakoshi, Y, Kaneko, M, Robert-Guroff, R C, Ting, R C, Gallo   +7 more
openaire   +2 more sources

Diagnosis of HAM/TSP based on CSF proviral HTLV-I DNA and HTLV-I antibody index

Neurology, 2001
The contribution of human T-cell lymphotropic virus (HTLV-I) DNA by PCR in CSF and the intrathecal synthesis of antibodies to HTLV-I by the antibody index (AI) to the diagnosis of HTLV-1-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) were evaluated. Cases of spastic paraparesis compatible with HAM/TSP had increased AI for HTLV-I (60/73)
M, Puccioni-Sohler, M, Rios, S M, Carvalho, R R, Gonçalves, C, Oliveira, R B, Correa, S, Novis, M S, de Oliveira, C, Bianco   +8 more
openaire   +2 more sources

Diversity of intrathecal antibody synthesis against HTLV-I and its relation to HTLV-I associated myelopathy

Journal of Neurology, 1996
The humoral immune response against human T-cell lymphotropic virus type I (HTLV-I) in the central nervous system (CNS) compartment and in the blood was investigated by enzyme immunoassay using 16 synthetic peptides corresponding to HTLV-I core and envelope sequences. We evaluated paired samples of cerebrospinal fluid and serum from HTLV-I seropositive
B, Kitze, K, Usuku, S, Izumo, M, Nakamura, H, Shiraki, S, Ijichi, S, Yashiki, T, Fujiyoshi, S, Sonoda, M, Osame   +9 more
openaire   +2 more sources

Antibodies to HTLV‐I in populations of the southwestern Pacific

Journal of Medical Virology, 1988
AbstractSera collected from 1,102 individuals in 14 populations of the southwestern Pacific between 1956 and 1979 were tested by ELISA for antibodies to human T‐cell leukemia virus type I (HTLV‐I). Selected sera were also tested by particle agglutination and immunoblotting.
David M. Asher, Jaap Goudsmit, Kitty L. Pomeroy, Ralph M. Garruto, Margreet Bakker, Steven G. Ono, Nicole Elliott, Keith Harris, Howard Askins, Zayd Eldadah, Adam D. Goldstein, D. Carleton Gajduek   +11 more
openaire   +3 more sources

Antibodies to HTLV-I in Japanese Immigrants in Brazil

JAMA: The Journal of the American Medical Association, 1986
To the Editor.— Human T-cell lymphotropic virus type I (HTLV-I), the causative agent of adult T-cell leukemia, is endemic in southern Japan, 1 the Caribbean islands, 2 and parts of Africa. 3 The prevalence of antibodies to HTLV-I is highest in Okinawa, Japan, where up to 31% of adults are seropositive in some regions. 4 Moreover, a high seroprevalence
T, Kitagawa, M, Fujishita, H, Taguchi, I, Miyoshi, H, Tadokoro   +4 more
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Adult T-Cell Leukemia with Anti-HTLV-I Antibody but No HTLV-I DNA in Tumor Cells

Acta Haematologica, 2001
Adult T-cell leukemia (ATL) is usually defined as a malignant disease of T cells infected by human T-lymphotropic virus type I (HTLV-I). In the present study, we describe a 49-year-old woman with an acute type ATL, whose leukemic cells do not contain the HTLV-I genome. Laboratory tests revealed an increase in abnormal lymphocytes with convoluted nuclei,
H, Fujiwara, N, Arima, T, Matsumoto, H, Ohtsubo, K, Matsushita, T, Kukita, C, Tei   +6 more
openaire   +2 more sources

Human T-Cell Leukemia Virus (HTLV-I) Antibodies in Africa

Science, 1984
Antibodies specific for human T-cell leukemia-lymphoma virus type I (HTLV-I) were demonstrated in serum samples from various groups of people in South Africa, Uganda, Ghana, Nigeria, Tunisia, and Egypt. The samples had been collected for other purposes and were presumably selected without bias toward clinical conditions associated with HTLV infections.
W. Saxinger, W. A. Blattner, P. H. Levine, J. Clark, R. Biggar, M. Hoh, J. Moghissi, P. Jacobs, L. Wilson, R. Jacobson, R. Crookes, M. Strong, A. A. Ansari, A. G. Dean, F. K. Nkrumah, N. Mourali, R. C. Gallo   +16 more
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High seroprevalence of anti–HTLV‐I antibody in rheumatoid arthritis

Arthritis & Rheumatism, 1996
AbstractObjective. To investigate the association between human T lymphotropic virus type I (HTLV‐I) infection and rheumatoid arthritis (RA) in Nagasaki, an area highly endemic for HTLV‐I infection.Methods. Sera from 113 female patients with RA and 19,796 female blood donors were screened for anti–HTLV‐I antibodies with a gelatin particle agglutination
K, Eguchi, T, Origuchi, H, Takashima, K, Iwata, S, Katamine, S, Nagataki   +5 more
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[HTLV-I antibody screening of blood donors].

Beitrage zur Infusionstherapie = Contributions to infusion therapy, 1992
Routine screening of 344,266 blood donations of approximately 200,000 donors for anti-HTLV-I was done by enzyme immuno assay (EIA). Repeatedly reactive samples were confirmed by Western Blot (WB) and radio immuno precipitation assay (RIPA). The prevalence of anti-HTLV-I in Bavarian blood donors is 0.02-0.026%. The specificity of HTLV-I-EIA is 99.95%.
G, Schwarzfischer, H, Schätzl, U, Bäcker, W, Weise, K, von der Helm, F, Deinhardt   +5 more
openaire   +1 more source