Results 81 to 90 of about 203,104 (241)

Equine herpesvirus 1 bridles T lymphocytes to reach its target organs [PDF]

, 2019
Equine herpesvirus 1 (EHV1) replicates in the respiratory epithelium and disseminates through the body via a cell-associated viremia in leukocytes, despite the presence of neutralizing antibodies. "Hijacked" leukocytes, previously identified as monocytic
Azab, Walid, Couck, Liesbeth, Favoreel, Herman, Laval, Kathlyn, Nauwynck, Hans, Poelaert, Katrien, Van Cleemput, Jolien, Van Den Broeck, Wim   +7 more
core   +1 more source

Molecular mechanistic insights into the OX40–OX40L complex from biophysical and computational analyses

Protein Science, Volume 35, Issue 1, January 2026.
Abstract OX40 and OX40L belong to the tumor necrosis factor receptor superfamily (TNFRSF) and tumor necrosis factor superfamily (TNFSF), respectively. Protein–protein interactions between OX40 and OX40L facilitate T cell responses, triggering various immunological and pathophysiological events.
Hiro Nishimuta, Akinobu Senoo, Keisuke Kasahara, Taito Kubo, Saeko Yanaka, Satoru Nagatoishi, Takanori So, Tadashi Ueda, Kouhei Tsumoto, Jose M. M. Caaveiro   +9 more
wiley   +1 more source

Immunofluorescence assay reactivity patterns of serum samples presenting indeterminate Western blot results for antibodies to HIV-1 and HTLV-I/II in Cordoba, Argentina

Revista do Instituto de Medicina Tropical de São Paulo, 2001
Serum samples (n: 110) from blood donors and high risk individuals from Cordoba, Argentina with indeterminate HIV-1 and HTLV-I/II Wb profiles were studied for specific antibodies to HTLV-I/II and HIV-1 by indirect immunofluorescence assay (IFA) and for ...
René GASTALDELLO, Sandra GALLEGO, María Beatriz ISA, Eduardo MATURANO, Santos SILEONI, Silvia NATES, Silvia MEDEOT   +6 more
doaj  

Molecular and Phylogenetic Evidence of Interfamilial Transmission of HTLV-1 in the Afro-Descendant Community of São José de Icatú in the Brazilian Amazon

Viruses
This study aimed to describe the prevalence of HTLV-1/2 in quilombola communities in the state of Pará and investigate the possible sociodemographic risk factors associated with the infection, as well as to trace the occurrence of the familial ...
Bruno José Sarmento Botelho, Wandrey Roberto dos Santos Brito, Gabriel dos Santos Pereira Neto, Janete Silvana Souza Gonçalves, Bruna Maria Silva Oliveira, Camille Marcela Camarinha de Oliveira, Aline Cecy Rocha de Lima, Sandra Souza Lima, Priscila de Nazaré Quaresma Pinheiro, Felipe Bonfim Freitas, João Farias Guerreiro, Ricardo Ishak, Antonio Carlos Rosário Vallinoto, Izaura M. Vieira Cayres Vallinoto   +13 more
doaj   +1 more source

Prevalence and risk factors for Human T-Lymphotropic Virus Type 1 (HTLV-1) among maintenance hemodialysis patients [PDF]

, 2017
BACKGROUND: Infection with the human T-cell lymphotropic virus type 1 (HTLV-1), although asymptomatic in most cases, can lead to potentially grave consequences, such as adult T-cell leukemia-lymphoma and HTLV-1-associated myelopathy / tropical spastic ...
Angiolina Kraychete, Antonio Alberto Lopes, Edgar M. Carvalho, Gildásio C. Conceição, Maria A. C. Penalva, Márcia S. Martins, Paulo Novis Rocha, Rilma F. S. Santos   +7 more
core   +1 more source

Increased Expression of Human T Lymphocyte Virus Type I (HTLV-I) Tax11-19 Peptide–Human Histocompatibility Leukocyte Antigen A*201 Complexes on CD4+ CD25+T Cells Detected by Peptide-specific, Major Histocompatibility Complex–restricted Antibodies in Patients with HTLV-I–associated Neurologic Disease

Journal of Experimental Medicine, 2004
Human T lymphocyte virus type I (HTLV-I)–associated chronic inflammatory neurological disease (HTLV-I–associated myelopathy/tropical spastic paraparesis [HAM/TSP]) is suggested to be an immunopathologically mediated disorder characterized by large ...
Y. Yamano, C. Cohen, N. Takenouchi, Karen Yao, U. Tomaru, Hong-Chuan Li, Y. Reiter, S. Jacobson   +7 more
semanticscholar   +1 more source

Human Spinal Cord GABAergic Neural Progenitor Cell

Cell Proliferation, Volume 59, Issue 2, February 2026.
Jia Xu, Xiaoqing Zhang, Aijin Ma, Jie Hao, Tianqing Li, Boqiang Fu, Lixiang Ma, Yan Liu, Peng Xiang, Kun Qian, Xiaohua Han, Yajie Li, Lijun Zhu, Qiyuan Li, Qiang Wei, Tingting Wu, Lei Wang, Jiani Cao, Ka Li, Hongling Zhao, ShuaiShuai Niu, Baoyang Hu, Tongbiao Zhao, Hong Chen   +23 more
wiley   +1 more source

ZNF282 Promotes Colorectal Cancer Progression Possibly via E2F1 Activation

Cancer Science, Volume 117, Issue 1, Page 90-104, January 2026.
ZNF282 is a zinc finger protein overexpressed in colorectal cancer that facilitates tumor progression by promoting cell cycle progression via E2F1 activation. Our study demonstrates that ZNF282 expression is associated with poor prognosis and may serve as a novel prognostic biomarker and therapeutic target. ABSTRACT Colorectal cancer (CRC) is a leading
Tadashi Abe, Takaaki Masuda, Taro Tobo, Masahiro Hashimoto, Yusuke Nakano, Hideyuki Saito, Takashi Ofuchi, Tomohiko Ikehara, Akinori Tsujimoto, Takafumi Nakano, Katsushi Dairaku, Junichi Takahashi, Kensuke Koike, Koto Kawata, Yuki Ando, Kiyotaka Hosoda, Takanari Tatsumi, Kosuke Hirose, Satoshi Higuchi, Hajime Otsu, Yusuke Yonemura, Ken Eto, Toru Ikegami, Koshi Mimori   +23 more
wiley   +1 more source

Harnessing controlled human infection models to accelerate vaccine development for neglected tropical diseases: Lessons from leishmaniasis

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Controlled Human Infection Models (CHIMs) offer a powerful approach to accelerate vaccine development for neglected tropical diseases (NTDs). This review highlights scientific and translational advances enabled by CHIMs, with a focus on a novel Leishmania major model.
Vivak Parkash
wiley   +1 more source

Antibody to Heat Shock Protein 70 (HSP70) Inhibits Human T-Cell Lymphoptropic Virus Type I (HTLV-I) Production by Transformed Rabbit T-Cell Lines

Toxins, 2012
Adult T cell leukemia is a fatal malignant transformation caused by the human T-cell lymphoptropic virus type I (HTLV-I). HTLV-I is only associated with the development of this disease in a small percentage of infected individuals.
Hanan Fallouh, Wahib Mahana
doaj   +1 more source