Results 131 to 140 of about 19,818 (181)
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The epidemiology of HTLV-I infection
Cancer Causes & Control, 1991It has been 10 years since the discovery of the human T-cell lymphotropic virus type I (HTLV-I), the first human retrovirus. During the past decade, significant progress has been made in understanding the transmission of the virus and defining its geographic distribution. It has been shown conclusively that HTLV-I is a causal factor in the induction of
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Evidence of HTLV-I Infection in Singapore Prostitutes
International Journal of STD & AIDS, 1991Sera obtained in 1987 from 63 male and 632 female Singapore prostitutes were screened for antibody to human T-cell leukaemia virus (HTLV)-I with a particle agglutination test. Of the 3 males and 4 females who were positive one had antibody to HTLV-I core and envelope antigen on Western Blot.
E H, Sng +5 more
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Possible association of HTLV-I infection and dementia
Acta Neurologica Scandinavica, 2009We report a Swedish patient with progressive dementia possibly associated with human T cell-lymphotropic virus type I (HTLV-I) infection. The clinical investigation revealed no typical sings of other neurological disorders. The patient was probably infected in East-Asia 35 years before onset of the disease.
J, Lycke +5 more
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Clinical and Molecular Parameters of HTLV-I Infection
Clinics in Laboratory Medicine, 1988The elucidation of the spread of HTLV-I through high-risk groups and the finite but real incidence of HTLV-I seropositivity in normal blood donor populations in the United States indicates that blood and blood products should be screened for this infectious agent.
G D, Ehrlich, B J, Poiesz
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Spastic paraparesis and HTLV-I infection in peru
Annals of Neurology, 1988Three of 6 patients with spastic paraparesis in Lima, Peru, were found to have antibodies to human T-lymphotropic virus type I (HTLV-I). Blood and cerebrospinal fluid antibodies were confirmed by Western blot analysis. Multilobulated lymphocytes in blood and cerebrospinal fluid of the index case stained with monoclonal antibodies for T-helper cells and
R T, Johnson +7 more
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Antibody profile of early HTLV-I infection
The Lancet, 1990To define the antibody profile of early seroconversion in infection with human T-cell lymphotropic virus type I (HTLV-I), consecutive serum samples from 10 subjects presumed to have seroconverted on the basis of the particle agglutination test were studied by three enzyme immunoassays and two confirmatory tests (radioimmunoprecipitation and western ...
Y M, Chen +6 more
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Cell Adhesion Molecules in HTLV-I Infection
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 1996Cell adhesion molecules expressed on the cell surface of leukemic cells and on vascular endothelial cells may play a key role in trafficking, localization, and infiltration of leukemic cells in adult T-cell leukemia (ATL). The predominant adhesion pathway between ATL cells or human T-cell leukemia virus type I (HTLV-I)-infected cell lines and human ...
T, Uchiyama, T, Ishikawa, A, Imura
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Effect of immunization on HTLV‐I infection in rabbits
International Journal of Cancer, 1989AbstractTwo groups of 3 rabbits, each immunized with heat‐inactivated HTLV‐I or a synthetic env peptide (env175‐l96), developed antibodies to viral proteins including gp68 and gp46. These immunized rabbits were then challenged with a transfusion of blood from HTLV‐I‐infected rabbits of the opposite sex.
N, Takehara +7 more
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Telomerase regulation in HTLV-I infection
Blood, 2008In this issue of Blood , Bellon and Nicot describe an elegant mechanism used by HTLV-I to up-regulate telomerase gene expression and function in the absence of the viral tax oncoprotein. Adult T-cell leukemia was first reported as an entity in Blood in 1977.[1][1] Three years later, Gallo et ...
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1991
Retroviruses are involved in many naturally occurring neoplasms in various animal species. Their involvement in human neoplasias has been the subject of extensive research, but not until the early 1980s was definitive evidence obtained for casual association of human retroviruses with a certain human disease.
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Retroviruses are involved in many naturally occurring neoplasms in various animal species. Their involvement in human neoplasias has been the subject of extensive research, but not until the early 1980s was definitive evidence obtained for casual association of human retroviruses with a certain human disease.
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