Results 81 to 90 of about 30,309 (229)
Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes. [PDF]
, 1995 Recently, a severe combined immunodeficiency syndrome with a deficiency of CD8+ peripheral T cells and a TCR signal transduction defect in peripheral CD4+ T cells was associated with mutations in ZAP-70.
Gelfand, EW +4 more
core +2 more sources
Helminths as architects of trained tolerance: implications for human health
Clinical &Translational Immunology, Volume 15, Issue 3, 2026.Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz +2 more
wiley +1 more source
iLABMED, Volume 4, Issue 1, Page 37-46, March 2026.This retrospective study analyzes the deferral reasons for 148,282 blood donors during 2019–2023 (overall deferral rate: 12.37%), identifying primary deferral reasons (e.g., elevated ALT for temporary deferral at 51.33%, HBsAg positivity for permanent deferral at 4.12%).
Limei Feng +5 more
wiley +1 more source
A patient with anti-NXP2-positive dermatomyositis and syphilis [PDF]
, 2020 Dermatomyositis is an auto-immune inflammatory myopathy that primarily affects the skin and muscle and can be triggered by exposure to various environmental factors.
Bovenberg, Maria Sarah Sophie +6 more
core
Choosing an allograft or autograft in orthopedic surgeries for athletes [PDF]
, 2016 Athletes and their doctors have the choice of using an allograft or autograft in reconstruction surgeries. The purpose of this study is to see if there is a difference in the healing mechanism and surgical outcome in using an allograft or autograft ...
Izzo, Cassandra M
core +1 more source
Immune Exhaustion in Chronic Infection and Cancer: Signaling Pathways and Therapeutic Interventions
MedComm, Volume 7, Issue 3, March 2026.Immune exhaustion is a well‐established hallmark of both cancer and chronic infection. This review proposes a novel “infection–exhaustion–tumor axis” framework, wherein chronic pathogens (e.g., oncogenic viruses) evade immune surveillance by hijacking inflammatory signaling to drive immune cell exhaustion, thereby creating immunosuppressive niches ...
Yali Song +10 more
wiley +1 more source
VirusesThis descriptive, observational, cross-sectional study evaluated HTLV-1 and HTLV-2 infections in Ananindeua, northern Brazil. Individuals were screened for anti-HTLV-1/2 using ELISA (Murex HTLV-I + II, DiaSorin).
Dara da Costa Soares +10 more
doaj +1 more source
Med Research, Volume 2, Issue 1, Page 75-88, March 2026.Using data from the Global Burden of Disease Study 2021, we systematically assessed leukemia prevalence and disability‐adjusted life years (DALYs) across 204 countries and territories from 1990 to 2021, stratified by subtype, demographics, and risk factors.
Yuping Wu +8 more
wiley +1 more source
HTLV-1/-2 and HIV-1 Co-infections: Retroviral Interference On Host Immune Status
Frontiers in Microbiology, 2013 The human retroviruses HIV-1 and HTLV-1/HTLV-2 share similar routes of transmission but cause significantly different diseases. In this review we have outlined the immune mediated mechanisms by which HTLVs affect HIV-1 disease in co-infected hosts ...
Elisabetta ePilotti +9 more
doaj +1 more source