No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Hoelzer Dieter +4 more
doaj +2 more sources
HTLV-II and Human Lymphoproliferative Disorders
HTLV-II is a rarely encountered human retrovirus that has been linked to atypical presentations of hairy-cell leukemia, as well as a variety of T-cell malignancies.
Golde, David W +2 more
core +3 more sources
Tuberculous meningoencephalomyelitis and coinfection with HTLV-I + HTLV-II: case report Meningoencefalomielite tuberculosa e coinfecção por HTLV-I + HTLV-II: relato de caso [PDF]
HTLV-I and HTLV-II are endemic in some areas of Brazil, where an associated disease, HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) have been diagnosed in significant number of infected individuals. Tuberculosis has been demonstrated
Marcio Menna-Barreto, Denise C. Machado
doaj +2 more sources
Prevalence of anti-HTLV-I & anti-HTLV-II antibodies in Blood donors in Bushehr Province
Human T-cll leukemia virus type 1 (HTLV-I) and HTLV-II are type C oncoviruses, members of the family Retroviridae. Blood transfusion is a transmission route. Screening for HTLV is routine in Khorasan Province/Iran.
Mahmood Reza Poukarim +3 more
doaj +1 more source
Molecular Evidence of Human T‑Cell Leukemia Virus Type 1 Transmission by Needlestick Injury in Healthcare Workers. [PDF]
ABSTRACT Human T‑cell leukemia virus type 1 (HTLV‑1) is a retrovirus that spreads primarily through cell‐to‐cell transmission. Occupational transmission of HTLV‐1 by needlestick injury is considered exceedingly rare, with no reported molecularly confirmed cases.
Tokunaga M +14 more
europepmc +2 more sources
The comparative molecular biology of HTLV-I and HTLV-II
The human T-cell leukemia viruses (HTLV) I and II, have been implicated in naturally occurring T-cell malignancies in man. We are engaged in ongoing comparative studies of HTLV-I and HTLV-II in our laboratory.
Rosenblatt, J +4 more
core +5 more sources
The Significance of cGAS-STING Signaling in Response to Oncogenic Viruses. [PDF]
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Guo L, Li L, Wang F, Liu W, Zhang Y.
europepmc +2 more sources
Plasma proteome analysis in HTLV-1-associated myelopathy/tropical spastic paraparesis [PDF]
Background: Human T lymphotropic virus Type 1 (HTLV-1) causes a chronic inflammatory disease of the central nervous system known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM) which resembles chronic spinal forms of multiple ...
Stumpf, M. P. H. (Michael P. H.) +43 more
core +1 more source
Pearson correlation coefficients and p-values for PVL versus age are shown for symptomatic and asymptomatic subjects (symptomatic group, solid lines; asymptomatic group, dashed lines).
Antoine Gessain (31917) +7 more
core +1 more source
HTLV-I/II and blood donors: determinants associated with seropositivity in a low risk population
OBJECTIVE: Blood donors in Brazil have been routinely screened for HTLV-I/II since 1993. A study was performed to estimate the prevalence of HTLV-I/II infection in a low risk population and to better understand determinants associated with seropositivity.
Soares Bernadette Catalan +2 more
doaj +3 more sources

