Results 51 to 60 of about 45,445 (214)

RNA‐Binding Proteins Shape Mammalian Retroelement RNA Fate: Lessons From HIV‐1, LINE‐1, and Related Reverse‐Transcribing Elements

Animal Research and One Health, EarlyView.
RNA‐binding proteins (RBPs) and RNA‐associated factors shape retroelement RNA fate by regulating RNA processing, translation, RNP assembly and remodeling, reverse transcription, nuclear trafficking, chromatin engagement, and RNA surveillance. These pathways balance productive retroviral replication or retrotransposon insertion with RNA decay ...
Mingrui Li, Zhangyuan Pan, Yongjuan Guan
wiley   +1 more source

Single-cell heterogeneity and cell-cycle-related viral gene bursts in the human leukaemia virus HTLV-1

Wellcome Open Research, 2017
Background: The human leukaemia virus HTLV-1 expresses essential accessory genes that manipulate the expression, splicing and transport of viral mRNAs. Two of these genes, tax and hbz, also promote proliferation of the infected cell, and both genes are ...
Martin R Billman, D. Rueda, C. Bangham
semanticscholar   +1 more source

Synergistic effects of HDAC inhibitor tucidinostat and ENT inhibitor dipyridamole in T-cell malignancies

Scientific Reports
Achieving both selectivity and cytotoxicity against cancer cells remains a major challenge in cancer therapy. Histone deacetylase (HDAC) inhibitors, such as tucidinostat, suppress tumor growth by epigenetically regulating tumor suppressor gene expression
Jiazhou Li, Ahmed E. Goda, Daniel Enriquez-Vera, Shuhei Fujii, Satomi Harazono, Jhajaira M. Araujo, Nao Nishikoba, Sophia Velarde, Atakan Zeki Namli, Alvaro De Jesus Huamani Ortiz, Shingo Nakahata   +10 more
doaj   +1 more source

Human T-lymphotropic virus infection and population characteristics of blood donors in Hainan

Zhongguo shuxue zazhi
[Objective] To investigate the prevalence of human T-lymphotropic virus (HTLV) infection among voluntary blood donors and provide reference for the development of blood safety screening strategy in Hainan Province.
HUANG Yiqing, HAN Hui, ZHANG Jiongjiong, ZHANG Yongli   +3 more
doaj   +1 more source

Fecal microbiota transplantation and microbiota‐based therapeutics in pediatric clinical practice: Current status and emerging indications

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Fecal microbiota transplantation (FMT) is a safe and effective treatment for recurrent or refractory Clostridioides difficile infection (rCDI) in children and adults. This review outlines the evidence behind FMT for rCDI, considerations in special pediatric populations, and limitations in current practice due to FMT access for patients under ...
Nikhil Pai, Maribeth Nicholson, Steven Rich, Máire A. Conrad   +3 more
wiley   +1 more source

NF-κB signaling mechanisms in HTLV-1-induced adult T-cell leukemia/lymphoma

The FEBS Journal, 2018
The human T‐cell leukemia virus type 1 (HTLV‐1) is a complex deltaretrovirus linked to adult T‐cell leukemia/lymphoma (ATLL), a fatal CD4 + malignancy in 3–5% of infected individuals.
E. Harhaj, C. Giam
semanticscholar   +1 more source

HTLV-1 proviral load of symptomatic patients.

, 2019
HTLV-1 proviral load of symptomatic patients.
Ariel Fridman (7961834), Natalia Altamirano (7961837), María Belén Bouzas (3150399), Carlos Remondegui (3909988), Lilia Mammana (715001), Luciana Tadey (7961846), Patricia Costantini (7961843), Mirta Remesar (7961831), Paula Aulicino (147850), Andrea Mangano (147875), María Verónica Pineda (7961828), Patricia Paradiso (7961840)   +11 more
core   +1 more source

Inhibition of Tunneling Nanotube (TNT) Formation and Human T-cell Leukemia Virus Type 1 (HTLV-1) Transmission by Cytarabine

Scientific Reports, 2018
The human T-cell leukemia virus type 1 (HTLV-1) is highly dependent on cell-to-cell interaction for transmission and productive infection. Cell-to-cell interactions through the virological synapse, biofilm-like structures and cellular conduits have been ...
M. Omsland, C. Pise-Masison, Dai Fujikawa, V. Galli, C. Fenizia, R. W. Parks, B. Gjertsen, G. Franchini, V. Andresen   +8 more
semanticscholar   +1 more source

Is the innate bio-protection power against human virus the same between males and females? A conclusion based on blood donor data of HTLV-I infection [PDF]

, 2008
Human T-cell leukemia virus type I (HTLV-I) is a retrovirus that causes adult T-cell leukemia. The male-to-female transmission is stronger than the reverse, so the carrier proportion of women is greater than that of men.
Minoru Tabata, Yasunori Higuchi, Nobuoki Eshima, Shigeru Karukaya   +3 more
core  

Leucemia/Linfoma T Seronegativo

Revista Digital de Postgrado
La leucemia/linfoma de células T del adulto (ATLL) es una neoplasia linfoproliferativa agresiva de linfocitos T CD4+/CD25+, asociada en más del 95 % de los casos a infección por HTLV-1, cuya seropositividad constituye un criterio diagnóstico esencial ...
Ligia Ramírez, Raul Strocchia, Zaidith Zerpa, Edgar García, Analiesse Marchan, Lucymar Escalona, Fernando Carrera, Sonia De Abreu   +7 more
doaj   +1 more source