Results 71 to 80 of about 45,445 (214)

Analysis of temporal expression of HTLV-2 reveals similarities and functional differences from HTLV-1 [PDF]

open access: yes, 2011
In the present study, we developed a robust splice site-specific real-time RT-PCR method to quantitate all HTLV-2 transcripts. Results of this analysis conducted on three different infected cell lines (HTLV-2A Mo-T , C344 and HTLV-2B BJAB-Gu) showed that
Bender Cecilia   +23 more
core   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

open access: yesImmunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu   +24 more
wiley   +1 more source

The Exceptional Oncogenicity of HTLV-1

open access: yesFrontiers in Microbiology, 2017
Human T-cell leukemia virus-1 (HTLV-1) is the first pathogenic human retrovirus identified in 1979 by the Gallo group. HTLV-1 causes fatal T-cell leukemia (adult T cell leukemia) and a progressive myelopahy (HTLV-1-associated myelopathy/ tropical spastic
Y. Tagaya, R. Gallo
semanticscholar   +1 more source

HTLV-1 Tax mutants that do not induce Garrest are disabled in activating the anaphase promoting complex-1

open access: yes, 2011
Copyright information:Taken from "HTLV-1 Tax mutants that do not induce Garrest are disabled in activating the anaphase promoting complex"http://www.retrovirology.com/content/4/1/35Retrovirology 2007;4():35-35.Published online 29 May 2007PMCID:PMC1894815.
Randall Merling (75706)   +6 more
core   +1 more source

Multi-HTLV results for HTLV/HCV co-infected samples.

open access: yes, 2021
Multi-HTLV results for HTLV/HCV co-infected samples.
Zhanna Kaidarova (346974)   +10 more
core   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

open access: yesJournal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag   +6 more
wiley   +1 more source

HTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma—A Tale of Two Proteins: Tax and HBZ

open access: yesViruses, 2016
HTLV-1 (Human T-cell lymphotropic virus type 1) is a complex human delta retrovirus that currently infects 10–20 million people worldwide. While HTLV-1 infection is generally asymptomatic, 3%–5% of infected individuals develop a highly malignant and ...
C. Giam, O. Semmes
semanticscholar   +1 more source

HTLV screening and confirmatory testing among blood donors in São Paulo: A cross‐sectional study

open access: yesTransfusion Medicine, EarlyView.
Abstract Introduction Human T‐cell lymphotropic virus types 1 and 2 (HTLV‐1/2) are transfusion‐transmissible retroviruses associated with severe diseases, and blood donor screening is mandatory in Brazil. Increasing HTLV‐related discard rates at our institution prompted this study to determine the prevalence and incidence of HTLV‐1/2 and to investigate
Suzete C. Ferreira   +11 more
wiley   +1 more source

Glucose Metabolism and Oxygen Availability Govern Reactivation of the Latent Human Retrovirus HTLV-1

open access: yesCell Chemical Biology, 2017
Summary The human retrovirus HTLV-1 causes a hematological malignancy or neuroinflammatory disease in ∼10% of infected individuals. HTLV-1 primarily infects CD4+ T lymphocytes and persists as a provirus integrated in their genome.
A. Kulkarni   +6 more
semanticscholar   +1 more source

HTLV-1+ subjects and PBMCs examined in this study.

open access: yes, 2019
HTLV-1+ subjects and PBMCs examined in this study.
Michi Miura (144400)   +5 more
core   +1 more source

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