Results 71 to 80 of about 45,959 (231)

Functional interactions of the Tax and p13 proteins of Human T-cell Leukemia Virus Type I [PDF]

open access: yes, 2013
Human T-cell leukemia virus type 1 (HTLV-1) establishes a lifelong persistent infection in humans. Approximately 3% of the infected individuals will develop adult T-cell leukemia/lymphoma (ATLL), an aggressive malignancy of mature CD4+ T-cells. The viral
Manicone, Mariangela
core  

HTLV-1-associated myelopathy in Spain

open access: yes, 2023
Background HTLV-1 infection is a neglected disease. Over 10 million people are infected worldwide, with hot spots of high endemicity across all continents.
Pozuelo, María José   +12 more
core   +1 more source

Cost-effectiveness of human T-cell leukemia virus type 1 (HTLV-1) antenatal screening for prevention of mother-to-child transmission.

open access: yesPLoS Neglected Tropical Diseases, 2023
BackgroundHuman T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL) and HTLV-1-associated myelopathy-tropical spastic paraparesis (HAM/TSP) with a poor prognosis.
Akiko Kowada
doaj   +1 more source

Development of Chimeric Antigen Receptor‐Modified NK Cells for the Immunotherapy of Adult T‐Cell Leukemia/Lymphoma

open access: yesEuropean Journal of Haematology, Volume 117, Issue 2, Page 481-491, August 2026.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase expression, representing a potentially tumor‐specific therapeutic target.
Yuichiro Uchida   +7 more
wiley   +1 more source

Disulfide-mediated apoptosis of human T-lymphotrophc virus type-I (HTLV-I)-infected cells in patients with HTLV-I-associated myelopathy/tropical spastic paraparesis. [PDF]

open access: yes, 2009
BACKGROUND: This study was conducted to construct a basis for a therapeutic strategy against human T-lymphotropic virus type-I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) using a compound that contained a disulfide moiety ...
Eguchi, Katsumi   +6 more
core  

Mimicry between HTLV-I and myelinbasicprotein: No response in HTLV-I-associatedmyelopathypatients

open access: yes, 1992
The reactivity to a peptide from the HTLV-I polyprotein (FKLPGLNSR) and a similar sequence from myelinbasicprotein (MBP) (FKLGGRDSR) was examined in relation to the proposal that mimicry of MBP by HTLV-I could be involved in autoimmune responses in HTLV ...
Carnegie, P.R.   +6 more
core   +1 more source

The m.14484T>C MT‐ND6 Mutation Presenting with a Hereditary Spastic‐Paraparesis Phenotype

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Gabriel Amorelli   +4 more
wiley   +1 more source

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia   +4 more
wiley   +1 more source

Screening transplant donors for HTLV-1 and -2

open access: yes, 2016
Human T-cell leukemia virus-1 (HTLV-1) is the first pathogenic human retrovirus discovered in 1980.1 HTLV-1 causes 2 devastating diseases: adult T-cell leukemia/lymphoma (ATL) and a neurological disorder, HTLV-1–associated myelopathy/tropical spastic ...
Willems, Luc   +3 more
core   +2 more sources

Anemia as a Public Health Issue in Mashhad, Iran: Evidence from the First Population-Based Study

open access: yesActa Medica Iranica, 2015
Anemia is one of the main conditions that impose an adverse impact on the socioeconomic state of any country; however, evidence on the prevalence of anemia is scant in Northeastern Iran.
Iman Eftekharzadeh-Mashhadi   +4 more
doaj  

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