Results 81 to 90 of about 68,004 (228)

Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission [PDF]

, 2013
Efficient HTLV-1 viral transmission occurs through cell-to-cell contacts. The Tax viral transcriptional activator protein facilitates this process. Using a comparative transcriptomic analysis, we recently identified a series of genes up-regulated in HTLV-
Afonso, PV, Brady, JN, Cachat, A, Chevalier, SA, Gessain, A, Mahieux, R, Pise-Masison, CA, Turpin, J   +7 more
core   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Prevalence of Human T-lymphotropic virus type 1 and 2 among blood donors in Manaus, Amazonas State, Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2017
Introduction: Human T-lymphotropic virus type 1 and 2 (HTLV-1/2) is endemic in Brazil, but few studies have investigated the seroprevalence of HTLV and its subtypes among blood donors in the capital city Manaus, Amazonas State, Brazil.
Márcia Poinho EncarnaçÃo de Morais, Cynara Melo Gato, Lucinei Alves Maciel, Pritesh Lalwani, Cristóvão Alves Costa, Jaila Dias Borges Lalwani   +5 more
doaj   +1 more source

Prevalence of Human T-Lymphotropic Virus Types I and II in Patients With Hematological Disorders in Isfahan, Iran [PDF]

, 2015
Background: Human T-cell lymphotropic virus types I and II (HTLV-I and HTLV-II) are deltaretroviruses which may cause leukemia, lymphoma and HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Ghorani, Mohammadreza., Karimi, Ali., Mahzoonieh, Mohamad Reza., Nikoozad, Razieh., Pourgheysari, Batoul.   +4 more
core   +3 more sources

Mechanistic role of GNE‐987 targeting BRD4‐HCP5 axis in pediatric T‐cell acute lymphoblastic leukemia

Journal of Cell Communication and Signaling, Volume 20, Issue 1, March 2026.
Abstract This study aims to explore the mechanism of action of the Bromodomain‐containing protein 4 (BRD4) inhibitor GNE‐987 in the treatment of pediatric T‐cell Acute Lymphoblastic Leukemia (T‐ALL), focusing on its effect in inhibiting T‐ALL cell proliferation by activating the HLA Complex P5 (HCP5) Super‐enhancer.
Xu Sang, Mengying Jiang, Yanchun Guan, Xin Chen, Zhen Zhang, Yumeng Wu, Wansheng Peng   +6 more
wiley   +1 more source

Prevalence of Hepatitis C Virus Infection in General Population of Mashhad, Northeastern Iran

Iranian Journal of Public Health, 2017
Background: Hepatitis C Virus (HCV) infection is one of the major blood-borne infections worldwide. HCV carriers may develop chronic hepatitis leading to liver cirrhosis and hepatocellular carcinoma (HCC).
Sanaz AHMADI GHEZELDASHT, Mohammad Reza HEDAYATI-MOGHADDAM, Khosro SHAMSIAN, Farhad FATHIMOGHADAM, Hamid Reza BIDKHORI, Seyed Abdolrahim REZAEE   +5 more
doaj  

Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages. [PDF]

, 1987
Primary human monocyte-derived macrophages (MDM) were shown to have diminished deoxynucleoside kinase activities compared to T lymphoblasts, and a reduced ability to phosphorylate dideoxynucleosides with anti-human immunodeficiency virus (HIV) activity ...
Carson, DA, Kornbluth, RS, Richman, DD
core  

Confirming the presence of HTLV-1 infection and the absence of HTLV-2 in blood donors from Arequipa, Peru Confirmação da presença de infecção por HTLV-1 e ausência de infecção por HTLV-2 em doadores de sangue de Arequipa, Peru

Revista do Instituto de Medicina Tropical de São Paulo, 2009
Epidemiological studies conducted in Peru disclosed HTLV-1 to be prevalent in different ethnic groups, and found HTLV-2 in some Amazonian Indians and in men who have sex with men.
Nadia Carmela Santos Quispe, Edwin Bengoa Feria, Elizabeth de los Santos-Fortuna, Adele Caterino-de-Araujo   +3 more
doaj   +1 more source

The zinc finger protein A20 inhibits TNF-induced NF-kappa B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappa B-inhibiting protein ABIN. [PDF]

, 1999
A
Ballard, Bandres, Barnes, Bergmann, Beyaert, Boldin, Cao, Carpentier, Chen, Chu, Cooper, Darnay, DeLamarter, De Valck, De Valck, Dignam, Dixit, Eckner, Ferran, Fukushi, Geleziunas, Gerritsen, Harris, Henkel, Heyninck, Hsu, Hsu, Hsu, Hu, Ishida, Ishida, Jäättelä, Kelliher, Krikos, Laherty, Laherty, LeBail, Lee, Malinin, Mercurio, Min, Muzio, Natoli, Naumann, Ng, Niederman, Niwa, Opipari, Perkins, Plaisance, Reinhard, Sarma, Schreck, Semmes, Song, Southern, Uhlik, Van Antwerp, Vandenabeele, Vanden Berghe, W., S. Plaisance, E. Boone, K. De Bosscher, M.L. Schmitz, W. Fiers, and G. Haegeman, Vanhaesebroeck, Van Snick, Vincenz, Yeh, Yin, Yurochko, Zandi, Zhang, Zhong, Zhong   +69 more
core   +2 more sources

Immune Exhaustion in Chronic Infection and Cancer: Signaling Pathways and Therapeutic Interventions

MedComm, Volume 7, Issue 3, March 2026.
Immune exhaustion is a well‐established hallmark of both cancer and chronic infection. This review proposes a novel “infection–exhaustion–tumor axis” framework, wherein chronic pathogens (e.g., oncogenic viruses) evade immune surveillance by hijacking inflammatory signaling to drive immune cell exhaustion, thereby creating immunosuppressive niches ...
Yali Song, Yazhi Mo, Si Chen, Yuemei Chen, Chunying Zhang, Shanying Deng, Juan Liao, Yi He, Wei Wang, Weidong Zheng, Tingting Zeng   +10 more
wiley   +1 more source