Results 211 to 220 of about 75,530 (296)

From Executor to Orchestrator: The Pharmacology Scientist in the Age of Agentic AI

Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 648-662, September 2026.
Drug development productivity has not improved despite five decades of computational advancement, with the probability that a compound entering Phase I achieving regulatory approval remaining near 10%. Each automation wave increased throughput while leaving the interpretive bottleneck intact; scientists continued to formulate questions, evaluate ...
Michael McCoy, Matthew McCoy
wiley   +1 more source

Disordered N-Terminal Tail "Wags the Dog" in Human Thymidylate Synthase. [PDF]

Biochemistry
Ricciardi MN, Sapienza PJ, Lee AL.
europepmc   +1 more source

First Taxonomically Curated DNA Barcode Reference Library for Polish Myriapods Fills an Important Knowledge Gap for Soil Invertebrates in Central Europe, Part I: Millipedes (Myriapoda: Diplopoda)

Ecology and Evolution, Volume 16, Issue 9, September 2026.
DNA barcoding enabled the creation of the first large, taxonomically verified barcode library for Polish millipedes, covering 981 individuals and 58 species (62% of the national fauna), with 468 COI sequences. The study reveals potential cryptic diversity, shifts in the Polish diplopod fauna and documents Melogona broelemanni as a species newly ...
Jakub Bienias, Łukasz Trębicki, Gabriela Karlik, Michał Grabowski   +3 more
wiley   +1 more source

Maternal circulating lipid metabolic heterogeneity in preeclampsia: machine learning identifies clinically distinct subtypes. [PDF]

BMC Pregnancy Childbirth
Gan J, Cao L, Shao J, Gu W, Hu R, Xiong Y, Wang Y, Zhao H, Zhou Q, Li X.   +9 more
europepmc   +1 more source

High and minimally variable adult marine survival among multiple stocks of Chinook salmon

Ecosphere, Volume 17, Issue 9, September 2026.
Abstract Estimates of individual survival across space and time provide critical information on processes that regulate population abundance. Here, we use state‐space models fit to data from more than 500 acoustically tagged Chinook salmon to better understand the factors that shape survival during the final summer and fall of marine residence—a life ...
Cameron Freshwater, Thomas Garrison, David D. Huff, Megan E. Moore, Noel Swain, Patrick L. Thompson, Catarina Wor   +6 more
wiley   +1 more source

Minimal disease detection by immunoglobulin high-throughput sequencing in pediatric Burkitt lymphoma. [PDF]

Blood Adv
Craig SM, Okeson KR, Adlowitz DG, Baker C, Rock PJ, Burack R, Fries C.   +6 more
europepmc   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, Volume 3, Issue 3, Page 444-465, September 2026.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

A Quantitative Assessment of Upper Limb Motor Function Across Disease Stages in Hereditary Transthyretin Amyloidosis. [PDF]

J Peripher Nerv Syst
Hamedani M, Prada V, Massucco S, Roveta E, Grandis M, Gemelli C, Schiavetti I, Signori A, Schenone C, Luigetti M, Guglielmino V, Sciarrone MA, Vitali F, Pradotto LG, Manganelli F, Tozza S, Palumbo G, Mazzeo A, Gentile L, Russo M, Luca M, D'Arma F, Pisciotta C, Fenu S, Pareyson D, Schenone A.   +25 more
europepmc   +1 more source

Method Matters: A Proteomics‐Informed Framework for Selecting Extracellular Vesicle Isolation Methods for Plasma

Journal of Extracellular Biology, Volume 5, Issue 9, September 2026.
This study evaluated 11 extracellular vesicle (EV) isolation methods which generate plasma‐derived EV‐containing preparations with varying degrees of contaminants. No single approach optimized purity and proteome coverage. In this paper we use proteomics to present an Evidence‐Based Framework to select plasma EV isolation methods based on downstream ...
Scheila Julia Werle, Marie Louise Nautrup Therkelsen, Chen Meng, Mads Grønborg, Lise Lotte Gluud, Dres Damgaard   +5 more
wiley   +1 more source

Sequence analysis of a viral strain isolated for the first time in the UK, clarifies the identity of a novel species of fabavirus. [PDF]

Arch Virol
Beddoe N, McGreig S, Fox A, Adams IP, Forsyth A.   +4 more
europepmc   +1 more source