Results 191 to 200 of about 69,047 (299)
Abstract Protein–protein interactions (PPIs) are shaped by evolutionary pressures that fine‐tune binding affinities and drive the epistatic relationships that support functional outcomes. Here, we used the complex of bovine pancreatic trypsin inhibitor (BPTI) and chymotrypsin as a model system to study how mutations at one or two positions affect ...
Noam Tzuri +3 more
wiley +1 more source
A two‐pronged screen of small molecules – (1) on recombinant kinin receptor and (2) through topical application – identifies kinin receptor antagonists, feeding behavior modulators, and new mosquitocidal molecules. Abstract BACKGROUND Aedes aegypti and Culex quinquefasciatus mosquitoes are primary vectors for numerous human and animal pathogens and ...
Bianca M. Henriques‐Santos +1 more
wiley +1 more source
Preparation of 1,2-Propanediol via One-Pot Reaction of Propylene and Hydrogen Peroxide Catalyzed by Hollow Titanium Silicalite and Sn‑β Catalyst. [PDF]
Ma D, Zhao Y, Peng X, Luo Y, Shu X.
europepmc +1 more source
ABSTRACT Plant‐based antioxidants are widely incorporated into foods to retard oxidative deterioration and to deliver health‐related benefits. Yet, their in‐product and in vivo performance frequently diverges from predictions based on solution‐phase chemical assays, because matrix interactions, processing history, and host metabolism reshape both ...
Márcio Vargas‐Ramella +6 more
wiley +1 more source
High-Throughput N-Glycan Analysis by IR-MALDESI With a 1.5-kHz Pulsed Mid-IR Laser. [PDF]
Eisenberg SM +5 more
europepmc +1 more source
ABSTRACT Persistent biodiversity data shortfalls undermine our capacity to detect species, map their distributions and characterize their spatial genetic structure, limiting robust biogeographic analyses and the development of effective conservation strategies.
I. Santos‐Perdomo +12 more
wiley +1 more source
Artificial intelligence-powered virtual standardized patients in teaching history-taking skills to medical students: a randomized controlled trial. [PDF]
Dang HNN +12 more
europepmc +1 more source
ABSTRACT Quantifying abundances of unicellular eukaryotes (protists) remains a central challenge in microbial ecology, as methodological differences can strongly influence abundance estimates and ecological interpretation. Although molecular tools have thus far greatly improved our understanding of protists, high rRNA gene copy numbers limit ...
Megan Gross +3 more
wiley +1 more source
Efficient Method for High-Throughput Screening of Compound Libraries Targeting Human PD-L1. [PDF]
Zamani MR +4 more
europepmc +1 more source

