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Identification of Novel Hub Genes and Potential Signaling Pathways with the Pathogenesis of Oral Cavity Squamous Cell Carcinoma Based on Bioinformatics Analysis. [PDF]

open access: yesCancer Inform
Eskandarion MR   +8 more
europepmc   +1 more source

Association analysis of hepatocellular carcinoma‐related hub proteins and hub genes

PROTEOMICS – Clinical Applications, 2023
AbstractPurposeHepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The occurrence and development of HCC are closely related to epigenetic modifications. Epigenetic modifications can regulate gene expression and related functions through DNA methylation.
Xinhong Zhang   +3 more
openaire   +2 more sources

RANKING DIFFERENTIAL HUBS IN GENE CO-EXPRESSION NETWORKS

Journal of Bioinformatics and Computational Biology, 2012
Identifying the genes that change their expressions between two conditions (such as normal versus cancer) is a crucial task that can help in understanding the causes of diseases. Differential networking has emerged as a powerful approach to detect the changes in network structures and to identify the differentially connected genes among two networks ...
Omar, Odibat, Chandan K, Reddy
openaire   +2 more sources

Hub Genes Identification in Brain Cancer with Gene Expression Data

2020 20th International Conference on Advances in ICT for Emerging Regions (ICTer), 2020
Central nervous system (CNS) cancers are one of the leading cancer types in the world. Analysing gene hubs involved in CNS cancer is important for predicting therapies. We have used gene expression data from one of the common brain cancer type (Pheochromocytoma /paraganglioma (PCPG)) for hub gene identification.
S. P. B. M Senadheera, A. R. Weerasinghe
openaire   +1 more source

Weighted gene co-expression network analysis for hub genes in colorectal cancer

Pharmacological Reports, 2023
This study is designed to explore hub genes participating in colorectal cancer (CRC) development through weighted gene co-expression network analysis (WGCNA).Expression profiles of CRC and normal samples were retrieved from the Gene Expression Omnibus (GEO) and the Cancer Genome Atlas (TCGA), and were subjected to WGCNA to filter differentially ...
Zheng Xu, Jianing Wang, Guosheng Wang
openaire   +2 more sources

Spatial organization of gene expression: the active chromatin hub

Chromosome Research, 2003
Developmental and tissue-specific expression of higher eukaryotic genes involves activation of transcription at the appropriate time and place and keeping it silent otherwise. Unlike housekeeping genes, tissue-specific genes generally do not cluster on the chromosomes.
de Laat, WL (Wouter), Grosveld, Frank
openaire   +3 more sources

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