Results 231 to 240 of about 8,236,393 (357)

Dual‐Organelle Secretome Conjugation and Organ‐Uptake Tracking (DuO‐SCOUT) Enables Deep and Sensitive Mapping of the Secreted Proteins

Advanced Science, EarlyView.
A novel dual‐organelle proximity labeling platform, DuO‐SCOUT, decodes the complex landscape of systemic organ‐organ communication by capturing both classical and unconventional secretomes. Application in metabolic models maps the adipose‐to‐brain secretory relay, identifying selective extra‐hypothalamic sites for adipose‐derived factors and expanding ...
Fenglian Yang, Rui Qian, Jiaxing Song, Xingqi Meng, Jin Young Kim, Kwok On Lai, Li Wang, Liang Zhang   +7 more
wiley   +1 more source

united-manufacturing-hub/united-manufacturing-hub: v0.11.0

<h1><a href="https://github.com/united-manufacturing-hub/united-manufacturing-hub/compare/v0.10.7...v0.11.0">0.11.0</a> (2024-03-01)</h1> <h3>Bug Fixes</h3> <ul> <li>define variable (<a href="https ...
kruegeralex, Matteo Danelon, Oto.Nak, fossabot, David Mackel, Ferdinand Linnenberg, JonaVo, Ricardo Christmann, Robert Feldmann, actions-user, Lukas Hennies, ONUR CAN KARAMAN, larswitte, Matthew Judijanto, Semantic Release Bot, Pascal Bro, AMINE AMAACH, Derek Tiffany, Arne, Patrick Melichar, chrisproch, felixmhofmann, Jeremy Theocharis   +22 more
core   +1 more source

The BTB/POZ‐MATH Protein ZmBPM1 Interacts With Autophagy‐related Protein ZmATG6 and Modulates the NLR Protein Rp1‐D21‐Mediated Defense Response in Maize

Advanced Science, EarlyView.
The maize BTB/POZ‐MATH (BPM) protein ZmBPM1 interacts with autophagy‐related protein ZmATG6 to relocate the NLR protein Rp1‐D21 from the nucleo‐cytoplasmic compartment into autophagosome‐like puncta, leading to autophagy‐mediated turnover and suppressing the hypersensitive response.
Chang‐Xiao Tang, Tong‐Tong Liu, Qi‐Dong Ge, Xiao‐Ying Liu, Wanxiao Wang, Yang Sun, Yanfei Liu, Faqiang Li, Guan‐Feng Wang   +8 more
wiley   +1 more source

Identification of psoriasis-associated hub genes by integrated transcriptomics and machine learning. [PDF]

Front Immunol
Zhao Y, Liang X, Tang M, Qiao L, Bai W, Huang C, Li M, Zeng X, Leng X.   +8 more
europepmc   +1 more source

united-manufacturing-hub/united-manufacturing-hub: v0.13.7

<h2><a href="https://github.com/united-manufacturing-hub/united-manufacturing-hub/compare/v0.13.6...v0.13.7">0.13.7</a> (2024-04-17)</h2> <h3>Bug Fixes</h3> <ul> <li>adjust docker images (<a href="https:/
kruegeralex, Matteo Danelon, Oto.Nak, fossabot, David Mackel, Ferdinand Linnenberg, JonaVo, Ricardo Christmann, Robert Feldmann, actions-user, Lukas Hennies, ONUR CAN KARAMAN, larswitte, Matthew Judijanto, Semantic Release Bot, Pascal Bro, AMINE AMAACH, Derek Tiffany, Arne, Patrick Melichar, chrisproch, felixmhofmann, Jeremy Theocharis   +22 more
core   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Identification of Hub Genes in Comorbidity of Psoriasis and Vitiligo Using Bioinformatics Analysis [PDF]

Chen Wang, Jinping Yuan, Huiwen Yu, Jiaying Lin, Bingxue Bai Department of Dermatology, The Second Affiliated Hospital of Harbin Medical University, Harbin, People’s Republic of ChinaCorrespondence: Bingxue Bai, Department of Dermatology, The Second ...
Bai B, Wang C, Lin J, Yuan J, Yu H
core  

PPI network and hub genes.

(A) PPI network constructed by STRING database; (B) top 10 Hub genes screened between CTEPH and control IPAH; (C) histogram of the top 10 Hub gene scores screened between CTEPH and control IPAH.
Liu Wang (213066), Shizhang Zhan (18120962), Ruoran Li (11652139), Wenping Wang (440405)   +3 more
core   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han, Guolin Miao, Yinqi Zhao, Zhiyong Du, Kaikai Lu, Changqi Xiao, Aiden Xian, Jiaxin Duanmu, Zihao Zhou, Jinxuan Chen, Lianxin Zhang, Chao Zhai, Yitong Xu, Zhaoling Li, Xianqin Shen, Sijing Shi, Jingxuan Chen, Si Mei, Yuan Fang, Liwen Zheng, Ling Zhang, Yuhui Wang, Wei Huang, Erdan Dong, Xunde Xian   +24 more
wiley   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source