Results 251 to 260 of about 198,026 (297)

Identification of empagliflozin-related hub genes in atherosclerosis and their correlations with immune infiltration: Network pharmacology and bioinformatics analyses. [PDF]

PLoS One
Rong Y, Liu X, Sun Y, Yang L, Chen L.
europepmc   +1 more source

A Virus‐Inducible E3–RLCK–MADS Module Coordinates Suppression of Plant Immunity and Fertility in Rice

Advanced Science, EarlyView.
ABSTRACT Viruses often hijack host developmental programs to promote infection, but the mechanistic links between reproductive regulation and antiviral immunity remain incompletely understood. Here, we identify a virus‐triggered hierarchical degradation cascade that links antiviral immunity and fertility regulation in rice. We show that the rice grassy
Yuansheng Wu, Fengling Wu, Shiting Huang, Denglu Yang, Xin Lei, Xue Zhang, Na Liu, Peng Gan, Chuan Li, Jie Zhang, Ming Wu, Qingxiao Jia, Shanshan Zhao, Jianguo Wu   +13 more
wiley   +1 more source

Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications. [PDF]

Mol Med Rep
Kang Q, Yuan P, Xie P, Xiao W, Dong L, Guan Z, Zhang K.   +6 more
europepmc   +1 more source

SERRATE Regulates Floral Meristem Activity by Antagonizing SHOOT MERISTEMLESS and Repressing Cytokinin Signaling

Advanced Science, EarlyView.
Floral meristem (FM) activity is crucial for the initiation of floral organs. In this study, SE represses IPT7 expression and cytokinin signaling via both the miR171c‐5p–KNAT2 and miR164c–CUC1/2–KNAT2 regulatory modules, thereby repressing FM activity. In contrast, STM induces both KNAT2 and IPT7 expression.
Wen Yang, Yiting Wang, Yuxin You, Zhiyue Wu, Dongbao Li, Xin Wang, Yongsheng Chang, Hang Zhao, Tao Zhu, Dijun Chen, Wei Chen, Bo Sun   +11 more
wiley   +1 more source

Computational analysis of hub genes associated with sarcopenia: integrative transcriptome insights from an Asian cohort. [PDF]

EXCLI J
Kim JG, Sharma AR, Lee YH, Kwon MJ, Chakraborty C, Kim JC, Jahr H, Lee SS.   +7 more
europepmc   +1 more source

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

Advanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao, Yuxuan Yang, Haosen Qiu, Jia Yang, Hao Liang, Zhaojun Jiang, Xiao Tong, Yongying Li, Qunfeng Huang, Jiaming Wu, Tian Lin, Jiang Yu, Min Liang   +12 more
wiley   +1 more source

Identification of Disulfidptosis-Associated Hub Genes in Psoriasis via Integrated Transcriptomic and Experimental Validation Approaches. [PDF]

J Cell Mol Med
Liu S, Chen T, Wu Y, Li F, Wang C, Lu C, Wang M.   +6 more
europepmc   +1 more source

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

Advanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che, Donghong Li, Huan Zhang, Tingting Xu, Juhan Li, Xuanzhou Chen, Louis D. Zhang, Shuguang Wang, Dianwen Song, Dongyong Sha   +9 more
wiley   +1 more source

Discovery Potential Hub Genes and Pathways in Keloid Fibroblast Development Based on Bioinformatics Analysis. [PDF]

Int J Genomics
Zhao B, Zhang W, Yao W, Li X, Yang T, Cheng H, Li X.   +6 more
europepmc   +1 more source

Identification of hub genes related to radiosensitivity and prognosis in rectal cancer. [PDF]

Transl Cancer Res
Yang H, Liu Y, Hao M, Li H, Yuan D, Ding L.   +5 more
europepmc   +1 more source