Results 131 to 140 of about 3,603,331 (295)

Structure‐function relationships of brazzein variants with altered interactions with the human sweet taste receptor [PDF]

, 2015
Kiran Kumar Singarapu, Marco Tonelli, John L. Markley, Fariba M. Assadi‐Porter   +3 more
openalex   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Fluorescence study of domain structure and lipid interaction of human apolipoproteins E3 and E4

, 2014
Chiharu Mizuguchi, Mami Hata, Padmaja Dhanasekaran, Margaret Nickel, Keiichiro Okuhira, Michael C. Phillips, Sissel Lund‐Katz, Hiroyuki Saito   +7 more
openalex   +2 more sources

Predicting invasions: alternative models of human‐mediated dispersal and interactions between dispersal network structure and Allee effects [PDF]

, 2012
Corey Chivers, Brian Leung
openalex   +1 more source

Characterization of dCas9 Interaction Kinetics and Local Chromatin Structure in Live Human Cells using Palm Superresolution Microscopy [PDF]

, 2020
Dushyant Mehra, Chiranjib Banerjee, Santosh Adhikari, Karl J. Clark, Stephen C. Ekker, Elias M. Puchner   +5 more
openalex   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Characterising the human-structure interaction effect of the Olympic Stadium in Cali, Colombia

Ingeniería e Investigación, 2009
This paper presents the results of analysing the human-structure interaction effect of the Olympic Stadium in Cali, Colombia. Acceleration in the southern and western grandstands due to ambient vibration, free vibration and forced vibration tests were ...
Albert Ricardo Ortiz, Daniel Gómez, Peter Thomson   +2 more
doaj  

Timing of human rhythmic jumping with vertical floor vibrations tends towards mechanically efficient solutions

Scientific Reports
Jumping on vibrating platforms is described not only by the frequency of jumping (FoJ) but also by the timing of key events in a cycle of jumping relative to vibrations. This study aimed to capture timing and efficiency-related adaptations during jumping
Nimmy Mariam Abraham, Stana Zivanovic, Genevieve Williams   +2 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Structured dataset of human-machine interactions enabling adaptive user interfaces [PDF]

, 2023
Angela Carrera-Rivera, Daniel Reguera-Bakhache, Félix Larrinaga, Ganix Lasa, Iñaki Garitano   +4 more
openalex   +1 more source