Results 61 to 70 of about 18,350,585 (254)

A Piecewise Stationary Spectral Model for Walking Crowd–Structure Interaction

Buildings
Pedestrian-induced vibration is a critical serviceability concern for flexible structures such as footbridges and long-span floors. Existing human–structure interaction models commonly rely on single-degree-of-freedom simplifications and time-domain ...
Jinping Wang, Gaoyang Zhu, Zekun Xu
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Human-human-robot interaction: robotic object’s responsive gestures improve interpersonal evaluation in human interaction

, 2020
Human-human-robot interaction: robotic object’s responsive gestures improve interpersonal evaluation in human ...
Adi Feiner (8484660), Guy Hoffman (8484663), Hadas Erel (8484657), Oren Zuckerman (8484666), Danielle Rifinski (8484654)   +4 more
core   +1 more source

Human–Structure Interaction Under Rhythmic Jumping: Model-Form Effects on Structural and Human Responses

Buildings
Stationary occupants modify the vibration of lightweight floors and grandstands, yet predicted responses depend on how the stationary human is represented.
Chunquan Zhao, Qingwen Zhang
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Optimization of a Human-Powered Aircraft Using Fluid–Structure Interaction Simulations

Aerospace, 2016
The special type of aircrafts in which the human power of the pilot is sufficient to take off and sustain flight are known as Human-Powered Aircrafts (HPAs).
Bob Vanderhoydonck, Gilberto Santo, Jan Vierendeels, Joris Degroote   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Designing for Conversational Interaction with Interactive Dance Works [PDF]

, 2011
In this paper we describe ongoing work, which explores the physicality of human-computer interaction in dance works. The use of physical simulations in the interface to connect with the performers and audiences lived experience of the physical world is ...
CLARKSON, D, Johnston, AJ
core  

Feminist Human-Robot Interaction]{Feminist Human-Robot Interaction : Disentangling Power, Principles and Practice for Better, More Ethical HRI

, 2023
Human-Robot Interaction (HRI) is inherently a human-centric field of technology. The role of feminist theories in related fields (e.g. Human-Computer Interaction, Data Science) are taken as a starting point to present a vision for Feminist HRI which can ...
Leite, Iolanda, McMillan, Donald, Harrison, Katherine,, Winkle, Katie,, Harrison, Katherine, Johnson, Ericka, Balaam, Madeline,, Arnelid, Maria, Winkle, Katie, Balaam, Madeline, Harrison, Katherine M., Arnelid, Maria,, Leite, Iolanda,, Johnson, Ericka,, McMillan, Donald,, Madeline Balaam, Donald McMillan, Maria Arnelid, Katherine Harrison, Katie Winkle, Iolanda Leite, Ericka Johnson   +21 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source