Results 101 to 110 of about 884,866 (255)

Navigating the nuances of studying animal facial behaviors with Facial Action Coding Systems

Frontiers in Ethology
Facial Action Coding Systems (FACS) are some of the most systematic and standardized methods for studying the physical aspects of animal facial behavior. Although FACS manuals provide some guidance on how to implement their coding system, they often lack
Brittany N. Florkiewicz, Brittany N. Florkiewicz   +1 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Comparative analysis of SLA-1 and SLA-2 genetic diversity in exotic, hybrid, and local pig breeds of Cameroon in relation to adaptive immunity against African swine virus

ImmunoInformatics
African swine fever is a severe hemorrhagic swine disease that greatly affects smallholder pig farm productivity in low-income countries as well as some developed countries.
Ebanja Joseph Ebwanga, Jess Bouhuijzen Wenger, Robert Adamu Shey, Nadine Buys, Rob Lavigne, Stephen Mbigha Ghogomu, Jan Paeshuyse   +6 more
doaj   +1 more source

Advancing Human-Animal Interaction to Counter Social Isolation and Loneliness in the Time of COVID-19: A Model for an Interdisciplinary Public Health Consortium. [PDF]

Animals (Basel), 2021
Hughes AM, Braun L, Putnam A, Martinez D, Fine A.   +4 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Detection and genetic diversity of Wolbachia and its associated prophage WO in mosquito populations from Ethiopia

Scientific Reports
Arboviral diseases transmitted by mosquitoes, including dengue, Chikungunya, Zika, yellow fever, West Nile virus (WNV), and Rift Valley fever (RVF), pose a significant public health challenge globally, particularly impacting populations in low and middle-
Samson Leta, Meskerem Mulisa Misgana, Bethel Befekadu Jaleta, Tesfaye Rufael Chibssa, Rob Lavigne, Jan Paeshuyse   +5 more
doaj   +1 more source

Spatiotemporal analysis and forecasting of lumpy skin disease outbreaks in Ethiopia based on retrospective outbreak reports

Frontiers in Veterinary Science
IntroductionLumpy skin disease is a viral disease that affects cattle belonging to genus Capripoxvirus (Poxviridae) and lead to significant economic losses.ObjectiveThe objective of this study was to evaluate the distribution of lumpy skin disease (LSD ...
Shimels Tesfaye, Shimels Tesfaye, Fikru Regassa, Fikru Regassa, Gashaw Beyene, Gashaw Beyene, Samson Leta, Samson Leta, Jan Paeshuyse   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source