Results 131 to 140 of about 12,981,608 (292)

Detection and genetic diversity of Wolbachia and its associated prophage WO in mosquito populations from Ethiopia

open access: yesScientific Reports
Arboviral diseases transmitted by mosquitoes, including dengue, Chikungunya, Zika, yellow fever, West Nile virus (WNV), and Rift Valley fever (RVF), pose a significant public health challenge globally, particularly impacting populations in low and middle-
Samson Leta   +5 more
doaj   +1 more source

Comparative analysis of SLA-1 and SLA-2 genetic diversity in exotic, hybrid, and local pig breeds of Cameroon in relation to adaptive immunity against African swine virus

open access: yesImmunoInformatics
African swine fever is a severe hemorrhagic swine disease that greatly affects smallholder pig farm productivity in low-income countries as well as some developed countries.
Ebanja Joseph Ebwanga   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Validation of the Human-Animal Interaction Scale (HAIS) in Czech Language. [PDF]

open access: yesInt J Environ Res Public Health, 2020
Machová K   +3 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Introduction to Human-Animal Interaction

open access: yes
Introduction to Human–Animal Interaction focuses on the human dimension of interacting with other animals. This book introduces recent developments, theories and debates in the relatively new research area of human–animal interaction (HAI) and focuses on the social and life sciences aspect of these interactions.
Laetitia Marechal, Emile van der Zee
openaire   +2 more sources

Human-Animal Welfare: The interconnectedness of human well-being and animal welfare

open access: yes
One Welfare is a concept that promotes the interconnection between human well-being, animal welfare and environmental sustainability. Therefore, the welfare of one influences the welfare of the others, and vice versa. Based on this approach, this chapter
Justine Cole (14211761)   +3 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

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