Results 131 to 140 of about 884,866 (255)

A Re-examination of Epistemological Paradigms Describing Animal Behavior in 8 Points. ‘Animal Consciousness and Science Matter’: a Reply

Relations, 2013
Roberto Marchesini
doaj   +1 more source

Can the treatment effects of human-animal interaction be maintained? A randomized controlled trial including follow-up in people with severe mental illness. [PDF]

Front Psychiatry
Schmid P, Tschöke S, Nauss C, Prinz P, Jauch-Ederer C, Kordeuter AL, Uhlmann C.   +6 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Exploring the Role of Cognitive Reserve and Human-Animal Interaction in Late-Life Depression: A Moderation Analysis. [PDF]

Geriatrics (Basel)
de Albuquerque NS, Sessegolo NS, Moret-Tatay C, Irigaray TQ.   +3 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Zoonotic Transmission of Soil-Transmitted Helminths in a Setting with Close Human-Animal Interaction: A Cross-Sectional Pilot Study from Meghalaya, India. [PDF]

Am J Trop Med Hyg
Mawrie UG, Manuel M, Marbaniang PJ, Sangriang IL, Laxmanan S, Ajjampur SSR, Sarkar R.   +6 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Editorial: Evidencing the impact of human-animal interaction for those living with mental health problems. [PDF]

Front Psychiatry
Shoesmith E, Hawkins RD, Ratschen E.
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Effects of human-animal interaction on salivary and urinary oxytocin in children and dogs. [PDF]

Psychoneuroendocrinology
Gnanadesikan GE, King KM, Carranza E, Flyer AC, Ossello G, Smith PG, Steklis NG, Steklis HD, Carter CS, Connelly JJ, Barnett M, Gee N, Tecot SR, MacLean EL.   +13 more
europepmc   +1 more source