Results 101 to 110 of about 15,477,856 (268)
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Nature Connections 2016 conference report: Implications for research and practice [PDF]
, 2017 A report of the key themes emerging from the Nature Connections 2016 conference drawing together researchers and practitioners from the field of human-nature ...
Hunt, Anne +3 more
core
Global SustainabilityNon-Technical Summary Fisheries encompass humans and fish, but fisheries researchers rarely model human–nature interactions over space and time. I filled this information gap for dolphinfish (Coryphaena hippurus), a popular, widely distributed species ...
Andrew K. Carlson
doaj +1 more source
A culturomics approach to quantifying the salience of species on the global internet
People and Nature, 2019 Conservation will only be successful over the long term if people support conservation goals. While many factors may influence the level of such support, it is clear that people are more willing to conserve species and places that they are familiar with ...
Richard J. Ladle +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Navigating human‐nature interactions by exploring plural values across ecosystem states
People and NatureSupporting biodiversity conservation in an effective and sustainable way requires addressing biodiversity loss while satisfying the dependency of people on nature.
K. C. Zoeller +5 more
doaj +1 more source
Sociobiotechnical systems: a new approach to humanity-nature interaction
Sociologicheskaja nauka i social'naja praktika, 2016 The concept of socio-bio-technical system (SBT-system) as an interdisciplinary theoretical instrument for analysis of utmost complex geosphere processes is offered and substantiated. The existing dichotomy concepts like ‘society-nature’, ‘rural-urban’, ‘local-global’ are not fit to integrated, controversial, mobile and not linear processes that are ...
openaire +3 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source