Advanced human organoid-on-chip with physiological cellular complexity reveals bidirectional secretion patterns. [PDF]
Hensel IV +4 more
europepmc +1 more source
Assembly of Cell‐Seeded 3D Printed Hydrogel Modules with Perfusable Channel Networks
Macroscale assembly was utilized to prepare perfusable tissue constructs from individually 3D printed hydrogel modules with embedded branched channel networks and port arrays for cell seeding. Novel multi‐material bioreactors were fabricated to facilitate the gluing of individual modules and the perfusion culture of assembled modular constructs seeded ...
Zachary J. Geffert +10 more
wiley +1 more source
Age-dependent neuroinflammatory effects of red blood cells and their exosomes in a human brain-on-chip model. [PDF]
Mehta-Doshi A +11 more
europepmc +1 more source
A MXene/PEDOT coating enables multimodal functionality and dual‐analyte detection of dopamine and serotonin in flexible microelectrode arrays while enhancing electrophysiological recording quality. The anti‐fouling, low‐impedance interface overcomes key limitations of conventional coatings, providing a robust and versatile platform to investigate the ...
Ilaria Gatti +8 more
wiley +1 more source
Redirecting the route: Monocyte-mediated delivery of oHSV-1 across a human BBB-on-chip model. [PDF]
Micheli S +6 more
europepmc +1 more source
Flexible piezoresistive pressure sensors underpin wearable and soft electronics. This review links sensing physics, including contact resistance modulation, quantum tunneling and percolation, to unified materials/structure design. We highlight composite and graded architectures, interfacial/porous engineering, and microstructured 3D conductive networks
Feng Luo +2 more
wiley +1 more source
Astrocyte-driven vasoconstriction impairs glymphatic clearance in a human tauopathy-on-chip model. [PDF]
Park R, Peng Y, Yslas AR, Lee E.
europepmc +1 more source
Cyclic Olefin Copolymers as Versatile Materials for Advanced Engineering Applications
Cyclic olefin copolymers (COCs) are presented as highly versatile materials combining tunable synthesis, excellent optical properties, and mechanical robustness. Their potential spans microfluidics, bioengineering, and advanced electronics, while emerging self‐healing and sustainable solutions highlight future opportunities.
Giulia Fredi +3 more
wiley +1 more source
Multiple structures of RNA polymerase II isolated from human nuclei by ChIP-CryoEM analysis. [PDF]
Kujirai T +12 more
europepmc +1 more source
Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip. [PDF]
Yadid M +12 more
europepmc +1 more source

