Results 201 to 210 of about 133,158,617 (301)

Sensor-integrated gut-on-a-chip for monitoring senescence-mediated changes in the intestinal barrier

The incidence of inflammatory bowel disease among the elderly has significantly risen in recent years, posing a growing socioeconomic burden to aging societies. Moreover, non-gastrointestinal diseases, also prevalent in this demographic, have been linked
Spitz, Sarah, Schobesberger, Silvia, Schuller, Patrick, Brandauer, Konstanze, Lorenz, Alexandra, Ertl, Peter, Frauenlob, Martin; orcid:   +6 more
core   +1 more source

Recent advances in immunocompetent human skin-on-chip models: Construction strategies and biomedical applications. [PDF]

Bioact Mater
Pang Y, Liu B, Jiang J, Wang CO, Zhang N, Guo X, Zeng Y, Ma H, Wang Z.   +8 more
europepmc   +1 more source

Single‐Cell Resolution Mapping of Osteoarthritis‐Associated Chondrocyte Dynamics Using a High‐Density CMOS MEA Platform

Advanced Healthcare Materials, EarlyView.
Single‐cell and spatially resolved impedance mapping using a high‐density CMOS‐MEA platform enables non‐invasive monitoring of osteoarthritis‐associated chondrocyte dynamics. Continuous label‐free measurements reveal heterogeneous remodeling behaviors, including proliferation, migration, and phenotypic transitions, establishing a powerful approach for ...
Neha Deshpande, Pauline Coquart, Bram Theuns, Susanne Cremery, Jaime Rodolfo V. Garcia III, Julien Verplanken, Dennis Lambrechts, Dries Braeken, Liesbet Lagae, Johanna Bolander   +9 more
wiley   +1 more source

<i>In vitro</i> recapitulation of intramuscular mRNA vaccination with naive and recall antigens using a human lymphoid follicle chip platform. [PDF]

iScience
Zhai Y, Ku MW, Yang K, Patil A, Prabhala P, He L, Man Y, Rahman M, Menon K, Spörri SB, Gharpure S, Isaacs AR, Ferdosi S, Pitek AS, Maruggi G, Bertholet S, Firestone J, Mousavi K, Miller E, Luisi K, Hellman CA, Williams LD, Tomaras GD, Yin P, Gygi SP, McAuliffe J, Ingber DE, Goyal G.   +27 more
europepmc   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Secondary bile acid lithocholic acid ameliorates colitis-like inflammation in a human intestine-on-chip system. [PDF]

Front Immunol
Kaden T, Allwang M, Stallhofer J, Graf K, Raasch M, Mosig AS.   +5 more
europepmc   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

The ethical aspects of human organ-on-chip models: A mapping review. [PDF]

Stem Cell Reports
Weidema J, de Vries M, Mummery C, de Graeff N.   +3 more
europepmc   +1 more source

NeuroVisio SyncPatch: A Skin‐Conformal Multimodal EMG–Motion Sensing Platform for Quantitative Neuromuscular Rehabilitation and Performance Monitoring

Advanced Healthcare Materials, EarlyView.
NeuroVisio SyncPatch integrates skin‐conformal electromyography (EMG) electrodes with camera‐tracked markers to jointly assess muscle activity and three‐dimensional knee kinematics during rehabilitation. Parallel feedback pathways provide real‐time kinematic guidance during movement and post‐trial neuromuscular feedback.
Bohyung Choi, Yoo‐Jin Jun, Heewon Choee, Kun‐Do Lee, Heesoo Kim, Yu Seok Hwang, Choong Yeon Kim, Seongok Chae, Juhyun Lee, Minkyu Je, Jae‐Woong Jeong, Hyung‐Soon Park   +11 more
wiley   +1 more source

Mucopenetrative Lipid-Polymer nanoparticles show Potent Anti-Inflammatory activity in a human Lung-on-Chip model. [PDF]

Int J Pharm
Perera KDC, Vasta AK, Menon JU.
europepmc   +1 more source