Results 181 to 190 of about 17,735,654 (311)

Trends in hospital deaths among human immunodeficiency virus–infected patients during the antiretroviral therapy era, 1995 to 2011

, 2015
Annie N. Cowell, Sheela Shenoi, Tassos C. Kyriakides, Gerald Friedland, Lydia Barakat   +4 more
openalex   +1 more source

RNA-Guided Human Genome Engineering via Cas9

Science, 2013
P. Mali, Luhan Yang, K. Esvelt, John D Aach, M. Guell, James E. DiCarlo, J. Norville, G. Church   +7 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

A non-coding RNA risk pathway in schizophrenia: miR-137 enhances the lncRNA GOMAFU through a pathological transcription network. [PDF]

Transl Psychiatry
Teng P, Zhou Y, Ji X, Li Y, Ku L, Wang F, Wen Z, Yao B, Feng Y.   +8 more
europepmc   +1 more source

Three-dimensional hard and soft tissue imaging of the human cochlea by scanning laser optical tomography (SLOT)

, 2017
N. Tinne, G. Antonopoulos, Saleh Mohebbi, J. Andrade, Lena Nolte, Heiko Meyer, Alexander Heisterkamp, Omid Majdani, Tammo Ripken   +8 more
openalex   +2 more sources

Magnetic resonance diffusion imaging of the human cervical spinal cord in vivo [PDF]

, 1999
Chris A. Clark, Gareth J. Barker, Paul S. Tofts   +2 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

In Vivo Quantification of White Matter Pathways in the Human Hippocampus. [PDF]

Hum Brain Mapp
Gumus M, Bourganos A, Mack ML.
europepmc   +1 more source

Roles of SLC/CCL21 and CCR7 in Human Kidney for Mesangial Proliferation, Migration, Apoptosis, and Tissue Homeostasis [PDF]

, 2002
Bernhard Banas, Markus Wörnle, Thorsten Berger, Peter J. Nelson, Clemens D. Cohen, Matthias Kretzler, Jochen Pfirstinger, Matthias Mack, Martin Lipp, Hermann‐Josef Gröne, Detlef Schlöndorff   +10 more
openalex   +1 more source

A Theory of Human Motivation

, 1943
A. Maslow
semanticscholar   +1 more source