Results 201 to 210 of about 1,861,346 (269)

Editorial: Degradation, conservation and ecological restoration of seagrass beds under intensifying global changes

Frontiers in Marine Science
Shaochun Xu, Shaochun Xu, Shaochun Xu, Shaochun Xu, Richard K. F. Unsworth, Richard K. F. Unsworth, Juan D. Gaitan-Espitia, Yi Zhou, Yi Zhou, Yi Zhou, Yi Zhou   +10 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Unraveling the invasion patterns of <i>Galinsoga quadriradiata</i> in mountain ranges: Insights from human activities, phenotypic and genetic variations. [PDF]

Plant Divers
Chen Y, Song X, Liu G, Wang J, Zhang C, Chang X, Zou J, Zhu Z.   +7 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Chemical characteristics of groundwater and surface water affected by human activities in the upper Jinzi River Basin, China. [PDF]

Sci Rep
Zhang X, Zhang Y, Gui Y, Sun R, Li J, Wu Q, Ding Y, Chen K.   +7 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Using Ecological Modeling to Study the Response of Distribution Dynamics of <i>Paraglenea fortunei</i> (Coleoptera: Cerambycidae) to Human Activities and Climate Change to in Northeast Asia. [PDF]

Ecol Evol
Wang P, Zhang L, Li J, Yang C, Xie G, Wang W.   +5 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Hydrochemical evolution and formation mechanism of groundwater affected by human activities in Zhangxuan basin, northwest of Yanshan mountains, China. [PDF]

PLoS One
Ma M, Yu Y, Yan B, Tuo Y, Gai J.
europepmc   +1 more source

Vision Sensor for Automatic Recognition of Human Activities via Hybrid Features and Multi-Class Support Vector Machine. [PDF]

Sensors (Basel)
Kamal S, Alhasson HF, Alnusayri M, Alatiyyah M, Aljuaid H, Jalal A, Liu H.   +6 more
europepmc   +1 more source