Results 111 to 120 of about 16,739,739 (312)

Semantics and syntax effects on event-related fields during speech comprehension: a MEG study

Frontiers in Human Neuroscience
IntroductionUnderstanding how the brain processes language during natural speech comprehension remains a key challenge. This study tested the feasibility of using an event-related field (ERF) approach to examine the spatiotemporal distribution of brain ...
Natalia Zhozhikashvili, Natalia Zhozhikashvili, Olga V. Sysoeva, Olga V. Sysoeva, Olga V. Sysoeva, Elizaveta Makarova, Olga V. Martynova, Olga V. Martynova   +7 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Long-range temporal correlations in resting state alpha oscillations in major depressive disorder and obsessive-compulsive disorder

Frontiers in Neuroinformatics
IntroductionMental disorders are a significant concern in contemporary society, with a pressing need to identify biological markers. Long-range temporal correlations (LRTC) of brain rhythms have been widespread in clinical cohort studies, especially in ...
Ekaterina Proshina, Olga Martynova, Olga Martynova, Galina Portnova, Guzal Khayrullina, Guzal Khayrullina, Olga Sysoeva, Olga Sysoeva   +7 more
doaj   +1 more source

Plan, activity, and intent recognition : theory and pratice /

, 2014
Plan recognition, activity recognition, and intent recognition together combine and unify techniques from user modeling, machine vision, intelligent user interfaces, human/computer interaction, autonomous and multi-agent systems, natural language ...
Sukthankar, Gita.
core  

Telomerase Activity is Downregulated Early During Human Brain Development

, 2016
Changes in hTERT splice variant expression have been proposed to facilitate the decrease of telomerase activity during fetal development in various human tissues.
Gabriele Saretzki, Abbas Ishaq, Christopher Morris, Peter Hanson   +3 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Real-time human activity recognition based on radar

, 2019
Most smart systems such as smart home and smart health respond to human's locations and activities. However, traditional solutions either require wearable sensors or lead to leaking privacy.
Guo, Hanqing
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source